Reactome | SRSF12 [nucleoplasm]

SRSF12 [nucleoplasm]

Stable Identifier

R-CFA-9770127

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

SRSF12, A0A8I3N395

Locations in the PathwayBrowser

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Metabolism of RNA (Canis familiaris)

- Processing of Capped Intron-Containing Pre-mRNA (Canis familiaris)
  - Formation of pre-mRNPs (Canis familiaris)
    - Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
      - nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
      - Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
  - mRNA 3'-end processing (Canis familiaris)
    - mRNA Polyadenylation (Canis familiaris)
      - Core CPA complex binds capped pre-mRNA (Canis familiaris)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
      - PP1 dephosphorylates RNA Pol II (Canis familiaris)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
      - RBBP6 activates CPSF complex (Canis familiaris)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
      - Recruitment of other CPA components to pre-mRNA-bound CPA core (Canis familiaris)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Canis familiaris)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
  - mRNA Splicing (Canis familiaris)
    - mRNA Splicing - Major Pathway (Canis familiaris)
      - Formation of the Spliceosomal C complex containing intron lariat (Canis familiaris)
        
        Spliceosomal B* complex [nucleoplasm] (Canis familiaris)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        Spliceosomal C complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
      - Formation of the Spliceosomal C* complex (Canis familiaris)
        
        Spliceosomal C complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        Spliceosomal C* complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
      - Formation of the Spliceosomal P complex and exon ligation (Canis familiaris)
        
        Spliceosomal C* complex [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)
        
        Spliceosomal P complex [nucleoplasm] (Canis familiaris)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Canis familiaris)
        
        Alternative Splicing Factors [nucleoplasm] (Canis familiaris)
        
        nonshuttling SRSFs [nucleoplasm] (Canis familiaris)
        
        SRSF12 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N395

Gene Names

SRSF12

Reference Genes

ENSEMBL:ENSCAFG00845006521.1

UCSC:A0A8I3N395 SRSF12

Other Identifiers

474992

Cfa.9490.1.A1_s_at

CfaAffx.5583.1.S1_at

GO:0000381

GO:0000395

GO:0003676

GO:0003723

GO:0065003

Participates

as a member of

nonshuttling SRSFs [nucleoplasm] (Canis familiaris)

Inferred From

SRSF12 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFP00845009043, ENSCAFG00845006521, ENSCAFT00845011574

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