Reactome | GHSR [plasma membrane]

GHSR [plasma membrane]

Stable Identifier

R-CFA-947659

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GHSR, F1PWC3

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PWC3

Gene Names

GHSR

Reference Genes

ENSEMBL:ENSCAFG00000015376

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000015376 GHSR

Other Identifiers

100101479

CfaAffx.23618.1.S1_at

GO:0000003

GO:0001616

GO:0003674

GO:0004930

GO:0005575

GO:0005886

GO:0006810

GO:0006950

GO:0007010

GO:0007165

GO:0007186

GO:0007267

GO:0008150

GO:0008154

GO:0008343

GO:0009058

GO:0009725

GO:0009755

GO:0009986

GO:0016020

GO:0016021

GO:0016520

GO:0022607

GO:0030252

GO:0032094

GO:0032100

GO:0032691

GO:0032715

GO:0032869

GO:0034330

GO:0040007

GO:0040018

GO:0042536

GO:0043005

GO:0043568

GO:0045121

GO:0046697

GO:0048856

GO:0050728

GO:0051963

Participant Of

hasMember

GPCRs that activate Gq/11 [plasma membrane]

hasComponent

Acyl ghrelin:GHSR [plasma membrane]

Inferred From

GHSR [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000121853

Ensembl

ENSCAFP00000022639, ENSCAFT00000024389, ENSCAFG00000015376

VGNC

41210