Reactome | GHSR [plasma membrane]

GHSR [plasma membrane]

Stable Identifier

R-CFA-947659

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GHSR, A5HKU8

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)
        
        GHSR [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A5HKU8

Gene Names

GHSR

Reference Genes

BioGPS Gene:100101479 GHSR

ENSEMBL:ENSCAFG00845025708.1

KEGG:cfa:100101479 GHSR

Monarch:100101479 GHSR

NCBI Gene:100101479 GHSR

UCSC:A5HKU8 GHSR

Reference Transcript

RefSeq:NM_001099945.1 GHSR

Other Identifiers

100101479

CfaAffx.23618.1.S1_at

GO:0001616

GO:0002031

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0008154

GO:0008343

GO:0009725

GO:0009755

GO:0009986

GO:0016020

GO:0016192

GO:0016520

GO:0030252

GO:0032094

GO:0032100

GO:0032691

GO:0032715

GO:0032720

GO:0032869

GO:0032870

GO:0040018

GO:0043005

GO:0043568

GO:0045121

GO:0046697

GO:0048009

GO:0048856

GO:0050728

GO:0051963

Participates

as a member of

GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)

as a component of

Acyl ghrelin:GHSR [plasma membrane] (Canis familiaris)

Inferred From

GHSR [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001093415.1

ENSEMBL

ENSCAFT00845045387, ENSCAFP00845035599, ENSCAFG00845025708

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