Reactome | activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane]

activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane]

Stable Identifier

R-CFA-936970

Type

Set [DefinedSet]

Species

Canis familiaris

Compartment

endosome membrane

Locations in the PathwayBrowser

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Participants

members

Participates

as an output of

Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Canis familiaris)

as an input of

IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Canis familiaris)

as a component of

activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Canis familiaris)

Inferred From

activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Homo sapiens)

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