Reactome | ERLIN1 [endoplasmic reticulum membrane]

ERLIN1 [endoplasmic reticulum membrane]

Stable Identifier

R-CFA-8866518

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum membrane

Synonyms

ERLIN1, A0A8I3NZK9

Locations in the PathwayBrowser

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Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Regulation of T cell activation by CD28 family (Canis familiaris)
    - Co-inhibition by PD-1 (Canis familiaris)
      - Regulation of PD-L1(CD274) expression (Canis familiaris)
        
        Regulation of PD-L1(CD274) Post-translational modification (Canis familiaris)
        
        AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) (Canis familiaris)
        
        Active transport of ubiquitinated CD274 from ER to cytosol (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)
        
        Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)
        
        Ubiquitination of CD274 by ERAD complex (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)
        
        Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)
        
        p-S195-CD274 binds ERAD complex (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERAD complex [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)
        
        ERLIN1 [endoplasmic reticulum membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NZK9

Gene Names

ERLIN1

Reference Genes

BioGPS Gene:609141 ERLIN1

ENSEMBL:ENSCAFG00845016181.1

KEGG:cfa:609141 ERLIN1

Monarch:609141 ERLIN1

NCBI Gene:609141 ERLIN1

UCSC:A0A8I3NZK9 ERLIN1

Reference Transcript

Other Identifiers

609141

CfaAffx.15056.1.S1_at

GO:0005783

GO:0005789

GO:0006629

GO:0008202

GO:0008203

GO:0008289

GO:0015485

GO:0016020

GO:0030163

GO:0031625

GO:0032933

GO:0032991

GO:0036503

GO:0045540

GO:0045541

GO:0045717

Participates

as a component of

ERLIN1:ERLIN2 [endoplasmic reticulum membrane] (Canis familiaris)

Inferred From

ERLIN1 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_038434443.1, XP_005637667.1, XP_038296197.1

ENSEMBL

ENSCAFT00845028793, ENSCAFG00845016181, ENSCAFP00845022659