Reactome | TMED10 [Golgi membrane]

TMED10 [Golgi membrane]

Stable Identifier

R-CFA-6808801

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

Golgi membrane

Synonyms

TMED10, A0A8I3NRF0

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPI-mediated anterograde transport (Canis familiaris)
        
        COPI vesicle uncoating (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPI-mediated anterograde transport (Canis familiaris)
      - COPI vesicle uncoating (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
      - cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Canis familiaris)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Canis familiaris)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [Golgi membrane] (Canis familiaris)
        
        TMED2:TMED10 tetramer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
    - Golgi-to-ER retrograde transport (Canis familiaris)
      - COPI-dependent Golgi-to-ER retrograde traffic (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Canis familiaris)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Canis familiaris)
        
        Golgi-to-ER cargo [Golgi membrane] (Canis familiaris)
        
        SURF4:p24 complex [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)
        
        p24 dimers [Golgi membrane] (Canis familiaris)
        
        TMED10 dimer [Golgi membrane] (Canis familiaris)
        
        TMED10 [Golgi membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NRF0

Gene Names

TMED10

Reference Genes

BioGPS Gene:610559 TMED10

ENSEMBL:ENSCAFG00845015221.1

KEGG:cfa:610559 TMED10

Monarch:610559 TMED10

NCBI Gene:610559 TMED10

UCSC:A0A8I3NRF0 TMED10

Reference Transcript

Other Identifiers

610559

Cfa.12999.1.S1_at

CfaAffx.26060.1.S1_s_at

GO:0005215

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006886

GO:0007030

GO:0008320

GO:0016020

GO:0016192

GO:0019905

GO:0030667

GO:0032732

GO:0035964

GO:0042589

GO:0043226

GO:0045055

GO:0048199

GO:0050714

GO:0055085

GO:0061024

GO:0070765

GO:0071806

GO:0106272

GO:0106273

GO:1902003

Participates

as a component of

Other forms of this molecule

TMED10 [ER to Golgi transport vesicle membrane]

TMED10 [endoplasmic reticulum membrane]

TMED10 [transport vesicle]

TMED10 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

TMED10 [Golgi membrane] (Homo sapiens)

Cross References

RefSeq

XP_038401229.1, XP_854043.1, XP_038530150.1

ENSEMBL

ENSCAFG00845015221, ENSCAFT00845027175, ENSCAFP00845021379

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