Reactome | phospho-POLR2A [nucleoplasm]

phospho-POLR2A [nucleoplasm]

Stable Identifier

R-CFA-6797701

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

p-3S-POLR2A, A0A8I3PKJ4

Locations in the PathwayBrowser

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Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional Regulation by TP53 (Canis familiaris)
      - TP53 Regulates Transcription of DNA Repair Genes (Canis familiaris)
        
        CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Canis familiaris)
        
        CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Canis familiaris)
        
        CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Canis familiaris)
        
        CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Canis familiaris)
        
        p-3S-RNA Pol II:TFIIF [nucleoplasm] (Canis familiaris)
        
        RNA Polymerase II holoenzyme complex phosphorylated by CDK12 [nucleoplasm] (Canis familiaris)
        
        phospho-POLR2A [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PKJ4

Gene Names

POLR2A

Reference Genes

BioGPS Gene:479483 POLR2A

ENSEMBL:ENSCAFG00845022622.1

KEGG:cfa:479483 POLR2A

Monarch:479483 POLR2A

NCBI Gene:479483 POLR2A

UCSC:A0A8I3PKJ4 POLR2A

Reference Transcript

Other Identifiers

479483

Cfa.1419.1.A1_at

Cfa.7393.1.A1_s_at

CfaAffx.25354.1.S1_s_at

GO:0000428

GO:0000791

GO:0001046

GO:0003676

GO:0003677

GO:0003824

GO:0003899

GO:0005634

GO:0005654

GO:0005665

GO:0005694

GO:0005737

GO:0006351

GO:0006366

GO:0016071

GO:0016740

GO:0016779

GO:0016787

GO:0042789

GO:0046872

GO:0140098

Participates

as a component of

RNA Polymerase II holoenzyme complex phosphorylated by CDK12 [nucleoplasm] (Canis familiaris)

Other forms of this molecule

POLR2A [nucleoplasm]

phospho-POLR2A [nucleoplasm]

Inferred From

p-3S-POLR2A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

XP_857844.4, XP_038521325.1, XP_038392602.1

ENSEMBL

ENSCAFT00845039960, ENSCAFG00845022622, ENSCAFP00845031290

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