Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TGFA [endoplasmic reticulum membrane]
Stable Identifier
R-CFA-5689476
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
endoplasmic reticulum membrane
Synonyms
TGFA precursor, A0A8I3Q314
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Transport to the Golgi and subsequent modification (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPII-mediated vesicle transport (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Loss of SAR1B GTPase (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Vesicle budding (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Cargo concentration in the ER (Canis familiaris)
CNIH1 binds TFGA and AREG precursors (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPII-mediated vesicle transport (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Loss of SAR1B GTPase (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Vesicle budding (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Cargo concentration in the ER (Canis familiaris)
CNIH1 binds TFGA and AREG precursors (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
Inner coat assembly and cargo binding (Canis familiaris)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
COPII cargo:receptors [endoplasmic reticulum membrane] (Canis familiaris)
CNIH1:TFGA,AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
TGFA [endoplasmic reticulum membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3Q314
Gene Names
TGFA
Reference Genes
ENSEMBL:ENSCAFG00845027844.1
UCSC:A0A8I3Q314 TGFA
Other Identifiers
403431
Cfa.133.1.S1_s_at
CfaAffx.5980.1.S1_at
GO:0005102
GO:0005576
GO:0005615
GO:0007165
GO:0008083
GO:0008284
GO:0016020
GO:0048018
GO:0051781
GO:0098772
Participates
as a member of
TFGA, AREG precursors [endoplasmic reticulum membrane] (Canis familiaris)
Other forms of this molecule
TGFA [clathrin-coated endocytic vesicle membrane]
TGFA [endoplasmic reticulum-Golgi intermediate compartment membrane]
TGFA [ER to Golgi transport vesicle membrane]
TGFA [extracellular region]
Inferred From
TGFA precursor [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
ENSEMBL
ENSCAFT00845049238
,
ENSCAFG00845027844
,
ENSCAFP00845038640
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
