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Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane]
Stable Identifier
R-CFA-5654330
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by FGFR (Canis familiaris)
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
PI-3K cascade:FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Negative regulation of FGFR4 signaling (Canis familiaris)
CBL ubiquitinates FRS2 and FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Activated FGFR4:p-FRS2 [plasma membrane]
(Canis familiaris)
phospho-p-Y542,Y580-PTPN11 [cytosol]
(Canis familiaris)
Participates
as an input of
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
as a component of
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Inferred From
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane]
(Homo sapiens)
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