Reactome | GRM1 [plasma membrane]

GRM1 [plasma membrane]

Stable Identifier

R-CFA-420521

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GRM1, A0A8I3NTE8

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Group I Metabotropic glutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Canis familiaris)
      - Metabotropic glutamate receptors bind glutamate (Canis familiaris)
        
        GRM1-8 [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)
        
        GRM1-8:L-Glu [plasma membrane] (Canis familiaris)
        
        GRM1-8 [plasma membrane] (Canis familiaris)
        
        GRM1,GRM5 [plasma membrane] (Canis familiaris)
        
        GRM1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NTE8

Gene Names

GRM1

Reference Genes

BioGPS Gene:484024 GRM1

ENSEMBL:ENSCAFG00845013661.1

Monarch:484024 GRM1

NCBI Gene:484024 GRM1

UCSC:A0A8I3NTE8 GRM1

Reference Transcript

Other Identifiers

484024

Cfa.9505.1.A1_at

CfaAffx.1457.1.S1_s_at

CfaAffx.1460.1.S1_at

CfaAffx.1460.1.S1_s_at

GO:0004930

GO:0005634

GO:0005886

GO:0007165

GO:0007186

GO:0007200

GO:0007206

GO:0007268

GO:0007626

GO:0008066

GO:0014069

GO:0016020

GO:0019233

GO:0030425

GO:0038037

GO:0038038

GO:0042391

GO:0042995

GO:0043005

GO:0043226

GO:0043410

GO:0045202

GO:0045211

GO:0050877

GO:0051930

GO:0055085

GO:0060078

GO:0071257

GO:0098685

GO:0098712

GO:0098872

GO:0098978

GO:0099530

GO:0099538

GO:0099566

Participates

as a member of

GRM1,GRM5 [plasma membrane] (Canis familiaris)

Inferred From

GRM1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_038382200.1, XP_038382199.1, XP_038510322.1, XP_038510323.1

ENSEMBL

ENSCAFT00845024382, ENSCAFP00845019164, ENSCAFG00845013661

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