Reactome | GRM3 [plasma membrane]

GRM3 [plasma membrane]

Stable Identifier

R-CFA-420509

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GRM3, A0A8I3N207

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Canis familiaris)
      - Metabotropic glutamate receptors bind glutamate (Canis familiaris)
        
        GRM1-8 [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)
        
        GRM1-8:L-Glu [plasma membrane] (Canis familiaris)
        
        GRM1-8 [plasma membrane] (Canis familiaris)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)
        
        GRM3 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N207

Gene Names

GRM3

Reference Genes

BioGPS Gene:100683236 GRM3

ENSEMBL:ENSCAFG00845006684.1

KEGG:cfa:100683236 GRM3

Monarch:100683236 GRM3

NCBI Gene:100683236 GRM3

UCSC:A0A8I3N207 GRM3

Reference Transcript

Other Identifiers

100683236

Cfa.20561.1.S1_at

CfaAffx.3592.1.S1_s_at

GO:0001641

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007193

GO:0007196

GO:0007216

GO:0008066

GO:0016020

GO:0051966

Participates

as a member of

GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Canis familiaris)

Inferred From

GRM3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_038412593.1, XP_038542212.1, XP_022282992.2

ENSEMBL

ENSCAFG00845006684, ENSCAFT00845011896, ENSCAFP00845009280