Reactome | S1PR2 [plasma membrane]

S1PR2 [plasma membrane]

Stable Identifier

R-CFA-419419

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

S1PR2, A0A8I3P3I1

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Lysosphingolipid and LPA receptors (Canis familiaris)
        
        S1PR2-5 bind S1P (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)
        
        S1PR2-5:S1P [plasma membrane] (Canis familiaris)
        
        S1PR2-5 [plasma membrane] (Canis familiaris)
        
        S1PR2 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3P3I1

Gene Names

S1PR2

Reference Genes

BioGPS Gene:484959 S1PR2

ENSEMBL:ENSCAFG00845018161.1

KEGG:cfa:484959 S1PR2

Monarch:484959 S1PR2

NCBI Gene:484959 S1PR2

UCSC:A0A8I3P3I1 S1PR2

Reference Transcript

Other Identifiers

484959

Cfa.14684.1.A1_at

Cfa.14684.1.A1_s_at

CfaAffx.27359.1.S1_at

GO:0001664

GO:0003376

GO:0004930

GO:0005178

GO:0005886

GO:0007165

GO:0007186

GO:0008528

GO:0016020

GO:0030036

GO:0038036

GO:0046847

GO:0060079

GO:0090394

GO:0098793

GO:0098794

GO:0098978

GO:0150052

GO:1903142

Participates

as a member of

S1PR2-5 [plasma membrane] (Canis familiaris)

Inferred From

S1PR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_038284599.1, XP_038423274.1, XP_022262773.1, XP_038423273.1, XP_038284598.1, XP_542076.1

ENSEMBL

ENSCAFP00845025110, ENSCAFT00845032140, ENSCAFP00845025126, ENSCAFG00845018161, ENSCAFT00845032117