Reactome | CHRM3 [plasma membrane]

CHRM3 [plasma membrane]

Stable Identifier

R-CFA-399994

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

CHRM3, A0A8I3N190

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Amine ligand-binding receptors (Canis familiaris)
        
        Muscarinic acetylcholine receptors (Canis familiaris)
        
        CHRM1,3,5 bind CHRM1,3,5 antagonists (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:CHRM1,3,5 antagonists [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 bind acetylcholine (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM3 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N190

Gene Names

CHRM3

Reference Genes

BioGPS Gene:403827 CHRM3

ENSEMBL:ENSCAFG00845002175.1

KEGG:cfa:403827 CHRM3

Monarch:403827 CHRM3

NCBI Gene:403827 CHRM3

UCSC:A0A8I3N190 CHRM3

Reference Transcript

Other Identifiers

403827

Cfa.12801.1.A1_s_at

Cfa.12801.1.A1_x_at

Cfa.3691.1.S1_s_at

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007213

GO:0016020

GO:0016323

GO:0016907

GO:0022600

GO:0030054

GO:0038023

GO:0045202

GO:0045211

GO:0045987

GO:0046541

GO:0095500

Participates

as a member of

CHRM1,3,5 [plasma membrane] (Canis familiaris)

Inferred From

CHRM3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_038342944.1, XP_038342923.1, XP_038342959.1, XP_038518353.1, XP_038518354.1, XP_038518359.1, XP_022273071.1, XP_038518352.1, XP_038518355.1, XP_038518356.1, XP_038389724.1, XP_038389723.1, XP_022273065.1, XP_038389725.1, XP_038518363.1, XP_038518361.1, XP_005618823.1, XP_038342879.1, XP_005618825.1, XP_022273063.1, XP_038389726.1, XP_038389728.1, XP_022273072.1, XP_038389729.1, XP_038389732.1, XP_038389730.1, XP_038518362.1, XP_038518360.1, XP_038389731.1, XP_038389727.1, XP_005618817.1, XP_038518358.1, XP_038518364.1, XP_038518357.1, XP_038389733.1, XP_038389735.1, XP_038389734.1, XP_038342935.1

ENSEMBL

ENSCAFG00845002175, ENSCAFT00845003817, ENSCAFP00845003034, ENSCAFT00845003811, ENSCAFP00845003039