Reactome | NTSR1 [plasma membrane]

NTSR1 [plasma membrane]

Stable Identifier

R-CFA-388916

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

NTSR1, A0A8I3S015

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Neurotensin receptors can bind neurotensins (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3S015

Gene Names

NTSR1

Reference Genes

BioGPS Gene:485963 NTSR1

ENSEMBL:ENSCAFG00845017702.1

Monarch:485963 NTSR1

NCBI Gene:485963 NTSR1

UCSC:A0A8I3S015 NTSR1

Reference Transcript

RefSeq:XM_038434300.1 NTSR1

Other Identifiers

485963

CfaAffx.19682.1.S1_at

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008344

GO:0010628

GO:0016020

GO:0016492

GO:0042802

GO:0043066

GO:0045121

Participates

as a member of

NTSR1,NTSR2 [plasma membrane] (Canis familiaris)

Inferred From

NTSR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_038290228.1

ENSEMBL

ENSCAFT00845031343, ENSCAFP00845024539, ENSCAFG00845017702