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CRK, CRKL [cytosol]
Stable Identifier
R-CFA-381945
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
Regulation of signaling by CBL (Canis familiaris)
CBL binds CRK (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
p(Y700,731,774)-CBL:CRK [cytosol] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
CBL:CRKL binds RAPGEF1 (Canis familiaris)
p(Y700,731,774)-CBL:CRK [cytosol] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Canis familiaris)
p(Y700,731,774)-CBL:CRK [cytosol] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by MET (Canis familiaris)
MET promotes cell motility (Canis familiaris)
MET activates RAP1 and RAC1 (Canis familiaris)
CRK,CRKL recruits RAC1 GEF to activated MET (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
DOCK7 activates RAC1 (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
GAB1 recruits CRK,CRKL to MET (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
RAPGEF1 activates RAP1 (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
RAPGEF1 binds CRK,CRKL (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
MET receptor recycling (Canis familiaris)
GGA3 associates with activated MET receptor (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Canis familiaris)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
Signaling by PDGF (Canis familiaris)
Downstream signal transduction (Canis familiaris)
Crk binds to the active PDGF receptor (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
p130Cas and C3G bind PDGFR bound Crk (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Canis familiaris)
CRK, CRKL [cytosol] (Canis familiaris)
Participants
members
CRKL [cytosol]
(Canis familiaris)
CRK [cytosol]
(Canis familiaris)
Participates
as an input of
GAB1 recruits CRK,CRKL to MET (Canis familiaris)
Crk binds to the active PDGF receptor (Canis familiaris)
CBL binds CRK (Canis familiaris)
as a component of
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Canis familiaris)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Canis familiaris)
p(Y700,731,774)-CBL:CRK [cytosol] (Canis familiaris)
Inferred From
CRK, CRKL [cytosol]
(Homo sapiens)
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