Reactome | GNAT3 [plasma membrane]

GNAT3 [plasma membrane]

Stable Identifier

R-CFA-380090

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GNAT3, A0A8I3PQY2

Locations in the PathwayBrowser

Expand all

Hemostasis (Canis familiaris)

- Platelet activation, signaling and aggregation (Canis familiaris)
  - Signal amplification (Canis familiaris)
    - ADP signalling through P2Y purinoceptor 12 (Canis familiaris)
      - Activated P2Y purinoceptor 12 binds G-protein Gi (Canis familiaris)
        
        ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GDP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GDP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
      - Dissociation of the P2Y purinoceptor 12:Gi complex (Canis familiaris)
        
        ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
      - Gi activation by P2Y purinoceptor 12 (Canis familiaris)
        
        ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GDP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)

Neuronal System (Canis familiaris)

- Transmission across Chemical Synapses (Canis familiaris)
  - Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
    - GABA receptor activation (Canis familiaris)
      - GABA B receptor activation (Canis familiaris)
        
        Activation of GABAB receptors (Canis familiaris)
        
        Adenylate cyclase inhibitory pathway (Canis familiaris)
        
        Adenylate cyclase increases the GTPase activity of G alpha-olf (Canis familiaris)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        Adenylate cyclase increases the GTPase activity of Gi alpha (Canis familiaris)
        
        (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GDP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        Dissociation of the Gi alpha:G olf complex (Canis familiaris)
        
        (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GDP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GDP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Canis familiaris)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Canis familiaris)
        
        G alpha (i): GTP [plasma membrane] (Canis familiaris)
        
        G alpha (i) [plasma membrane] (Canis familiaris)
        
        GNAT3 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PQY2

Gene Names

GNAT3

Reference Genes

BioGPS Gene:491406 GNAT3

ENSEMBL:ENSCAFG00845025682.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025682.1 GNAT3

KEGG Gene (Canis lupus familiaris):491406 GNAT3

Monarch:491406 GNAT3

NCBI Gene:491406 GNAT3

Reference Transcript

RefSeq:XM_844573.3 GNAT3

Other Identifiers

491406

CfaAffx.21125.1.S1_at

GO:0003824

GO:0003924

GO:0005525

GO:0005737

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007188

GO:0016787

GO:0019001

GO:0023052

GO:0031683

GO:0032991

GO:0050877

GO:0050909

GO:0050913

GO:0050916

GO:0050917

Participates

as a component of

as a member of

G alpha (i) [plasma membrane] (Canis familiaris)

Inferred From

GNAT3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_849666.1

OpenTargets

ENSG00000214415

Ensembl

ENSCAFT00845045361, ENSCAFG00845025682, ENSCAFP00845035579

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