Reactome | BDKRB1 [plasma membrane]

BDKRB1 [plasma membrane]

Stable Identifier

R-CFA-374257

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

BDKRB1, Q9BDQ5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Bradykinin receptors B1 and B2 bind to bradykinin (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Canis familiaris)
        
        Bradykinin receptor [plasma membrane] (Canis familiaris)
        
        BDKRB1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:Q9BDQ5

Gene Names

BDKRB1

Reference Genes

BioGPS Gene:490847 BDKRB1

ENSEMBL:ENSCAFG00030008931

KEGG:cfa:490847 BDKRB1

Monarch:490847 BDKRB1

NCBI Gene:490847 BDKRB1

UCSC:Q9BDQ5 BDKRB1

Reference Transcript

Other Identifiers

490847

CfaAffx.3.1.S1_s_at

GO:0004930

GO:0004947

GO:0006954

GO:0007186

GO:0009612

GO:0016020

GO:0032496

GO:0042277

Participates

as a member of

Bradykinin receptor [plasma membrane] (Canis familiaris)

Inferred From

BDKRB1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001014306.1, XP_038528850.1

ENSEMBL

ENSCAFP00845005045, ENSCAFG00845003563, ENSCAFT00845006349

ZINC - Substances

BKRB1_CANLF

ZINC target

Q9BDQ5

PRO

Q9BDQ5

ZINC - Predictions - Purchasable

BKRB1_CANLF

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