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phospho-FRS2 [cytosol]
Stable Identifier
R-CFA-190355
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
p-6Y-FRS2, A0A8I3P4L9
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
Frs2-mediated activation (Canis familiaris)
FRS2 is phosphorylated by active TrkA receptor (Canis familiaris)
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Canis familiaris)
phospho-FRS2 [cytosol] (Canis familiaris)
p-FRS2:CRKL binds C3G (Canis familiaris)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Canis familiaris)
phospho-FRS2 [cytosol] (Canis familiaris)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Canis familiaris)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Canis familiaris)
phospho-FRS2 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3P4L9
Gene Names
FRS2
Reference Genes
BioGPS Gene:474444 FRS2
ENSEMBL:ENSCAFG00845017484.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845017484.1 FRS2
KEGG Gene (Canis lupus familiaris):474444 FRS2
Monarch:474444 FRS2
NCBI Gene:474444 FRS2
Reference Transcript
RefSeq:XM_005625613.2 FRS2
RefSeq:XM_005625611.1 FRS2
RefSeq:XM_005625610.2 FRS2
RefSeq:XM_005625612.2 FRS2
Other Identifiers
474444
Cfa.19573.1.S1_at
Cfa.1958.1.S1_at
Cfa.1958.2.A1_at
CfaAffx.1604.1.S1_s_at
GO:0001702
GO:0001759
GO:0002088
GO:0003281
GO:0005068
GO:0005104
GO:0005168
GO:0005737
GO:0005886
GO:0005911
GO:0005912
GO:0007169
GO:0007405
GO:0008543
GO:0008595
GO:0012501
GO:0022414
GO:0023052
GO:0030154
GO:0030900
GO:0042981
GO:0043410
GO:0046619
GO:0048856
GO:0050678
GO:0060090
GO:0060527
GO:0070307
GO:0070372
GO:2000726
Participates
as a component of
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Canis familiaris)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Canis familiaris)
Other forms of this molecule
phospho-FRS2 [cytosol]
FRS2 [cytosol]
phospho-FRS2 [plasma membrane]
FRS2 [plasma membrane]
phospho-FRS2 [plasma membrane]
Inferred From
p-6Y-FRS2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 436 (in Homo sapiens)
Coordinate
436
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 196 (in Homo sapiens)
Coordinate
196
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 306 (in Homo sapiens)
Coordinate
306
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 349 (in Homo sapiens)
Coordinate
349
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 392 (in Homo sapiens)
Coordinate
392
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 471 (in Homo sapiens)
Coordinate
471
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_005625668.1
,
XP_005625669.1
,
XP_005625667.1
,
XP_005625670.1
OpenTargets
ENSG00000166225
Ensembl
ENSCAFG00845017484
,
ENSCAFT00845030983
,
ENSCAFP00845024277
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