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About
What is Reactome ?
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RBX1 [cytosol]
Stable Identifier
R-CFA-180582
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
RBX1, A0A8I3NXW3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Canis familiaris)
Formation of the SCF-FBXL7 complex (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Canis familiaris)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF-FBXL18 ubiquitinates FBXL7 (Canis familiaris)
SKP1:CUL1:RBX1:FBXL18 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF-FBXL7 ubiquitinates AURKA (Canis familiaris)
SCF-FBXL7:AURKA [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF:FBXL7 binds AURKA (Canis familiaris)
SCF-FBXL7:AURKA [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
KEAP1-NFE2L2 pathway (Canis familiaris)
CUL3:RBX1 ubiquitinates KEAP1 (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Canis familiaris)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
MAP1LC3B binds KEAP1 and SQSTM1 (Canis familiaris)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Canis familiaris)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Canis familiaris)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Canis familiaris)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3 dissociates from forming autophagosome (Canis familiaris)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Canis familiaris)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Canis familiaris)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SESN1,SESN1 bind SQSTM1 and KEAP1 (Canis familiaris)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Cellular response to hypoxia (Canis familiaris)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Canis familiaris)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Canis familiaris)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Proteasome proteolyzes ub-HIF-alpha (Canis familiaris)
VBC complex (with or without LIMD1) [cytosol] (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Canis familiaris)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Class I MHC mediated antigen processing & presentation (Canis familiaris)
Antigen processing: Ubiquitination & Proteasome degradation (Canis familiaris)
Interaction of E3 with substrate and E2-Ub complex (Canis familiaris)
Ag-substrate:E3:E2:Ub [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Polyubiquitination of substrate (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
E3:K48-polyubiquitinated substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
E3:Ub:substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Release of E3 from polyubiquitinated substrate (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
E3:K48-polyubiquitinated substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Transfer of Ub from E2 to substrate and release of E2 (Canis familiaris)
Ag-substrate:E3:E2:Ub [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
E3:Ub:substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Prolactin receptor signaling (Canis familiaris)
PRLR binds SCF beta-TrCP complex (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Prolactin receptor is internalized (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Prolactin receptor ligands bind the prolactin receptor (Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Neddylation (Canis familiaris)
26S proteasome degrades HIFalpha (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Canis familiaris)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
NEDD8-CRL1 E3 ligase complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-CRL2 E3 ligase complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-CUL3:RBX1:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Canis familiaris)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Canis familiaris)
CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Canis familiaris)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Canis familiaris)
CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Canis familiaris)
CRL E3 ubiquitin ligases [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Canis familiaris)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
NEDD8-CRL1 E3 ligase complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-CRL2 E3 ligase complex [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-CUL3:RBX1:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CUL9:RBX1 ubiquitinates BIRC5 (Canis familiaris)
NEDD8-CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1:CUL7:CCDC8:OBSL1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Canis familiaris)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 (Canis familiaris)
NEDD8-CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1:CUL7:CCDC8:OBSL1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Canis familiaris)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Canis familiaris)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Canis familiaris)
CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Canis familiaris)
CUL9:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Canis familiaris)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Hedgehog (Canis familiaris)
Hedgehog 'off' state (Canis familiaris)
Degradation of GLI1 by the proteasome (Canis familiaris)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
GLI3 is processed to GLI3R by the proteasome (Canis familiaris)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Signaling by WNT (Canis familiaris)
Degradation of beta-catenin by the destruction complex (Canis familiaris)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Degradation of ubiquitinated beta catenin by the proteasome (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Canis familiaris)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Degradation of DVL (Canis familiaris)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Canis familiaris)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Canis familiaris)
CUL3:KLHL12:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Canis familiaris)
CUL3:KLHL12:RBX1 [cytosol] (Canis familiaris)
RBX1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NXW3
Gene Names
RBX1
Reference Genes
BioGPS Gene:474494 RBX1
ENSEMBL:ENSCAFG00845019033.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845019033.1 RBX1
Monarch:474494 RBX1
NCBI Gene:474494 RBX1
Reference Transcript
RefSeq:XM_531722.5 RBX1
Other Identifiers
474494
Cfa.2549.1.A1_s_at
GO:0000209
GO:0002376
GO:0003824
GO:0004842
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006511
GO:0006513
GO:0007283
GO:0008270
GO:0016567
GO:0016740
GO:0019005
GO:0022414
GO:0023052
GO:0030163
GO:0031146
GO:0031461
GO:0031462
GO:0031463
GO:0031464
GO:0031465
GO:0031466
GO:0031467
GO:0031625
GO:0032436
GO:0032480
GO:0034450
GO:0036211
GO:0042110
GO:0043123
GO:0043161
GO:0043226
GO:0045116
GO:0045732
GO:0046872
GO:0061629
GO:0061630
GO:0061663
GO:0070936
GO:0071230
GO:0097602
GO:0140096
GO:0140627
GO:1902499
GO:1904263
Participates
as a component of
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
NEDD8-CUL9:RBX1 [cytosol] (Canis familiaris)
CUL9:RBX1 [cytosol] (Canis familiaris)
CRL2 E3 ubiquitin ligase [cytosol] (Canis familiaris)
NEDD8-CRL1 E3 ligase complex [cytosol] (Canis familiaris)
NEDD8-CUL3:RBX1:BTB [cytosol] (Canis familiaris)
NEDD8-CRL2 E3 ligase complex [cytosol] (Canis familiaris)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Canis familiaris)
CUL3:KLHL12:RBX1 [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Canis familiaris)
SKP1:CUL1:RBX1:FBXL18 [cytosol] (Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
SCF E3 ubiquitin ligase [cytosol] (Canis familiaris)
RBX1:CUL3:BTB [cytosol] (Canis familiaris)
RBX1-CUL2-EloB,C-VHL [cytosol] (Canis familiaris)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Canis familiaris)
Cul5-SCF complex [cytosol] (Canis familiaris)
as an input of
Formation of the SCF-FBXL7 complex (Canis familiaris)
Other forms of this molecule
RBX1 [nucleoplasm]
Inferred From
RBX1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_531722.2
OpenTargets
ENSG00000100387
Ensembl
ENSCAFP00845026293
,
ENSCAFG00845019033
,
ENSCAFT00845033585
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