Reactome | NDUFA10 [mitochondrial inner membrane]

NDUFA10 [mitochondrial inner membrane]

Stable Identifier

R-CFA-163937

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial inner membrane

Synonyms

NDUFA10, A0A8I3Q997

Locations in the PathwayBrowser

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Metabolism (Canis familiaris)

- Aerobic respiration and respiratory electron transport (Canis familiaris)
  - Respiratory electron transport (Canis familiaris)
    - Complex I biogenesis (Canis familiaris)
      - Intermediate 1 binds HP subcomplex to form Intermediate 2 (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)
      - Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)
      - The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)
        
        980kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)
        
        Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)
    - Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Canis familiaris)
      - Complex I [mitochondrial inner membrane] (Canis familiaris)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Canis familiaris)
        
        HP subcomplex [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)
        
        NDUFA10 [mitochondrial inner membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3Q997

Gene Names

NDUFA10

Reference Genes

BioGPS Gene:608244 NDUFA10

ENSEMBL:ENSCAFG00845030335.1

Monarch:608244 NDUFA10

NCBI Gene:608244 NDUFA10

UCSC:A0A8I3Q997 NDUFA10

Reference Transcript

Other Identifiers

608244

Cfa.10289.1.S1_at

CfaAffx.19535.1.S1_s_at

GO:0005739

GO:0005743

GO:0005759

GO:0006091

GO:0006120

GO:0008137

GO:0016491

GO:0045271

GO:0055085

GO:1902600

Participates

as a component of

NDUFA10:FAD [mitochondrial inner membrane] (Canis familiaris)

Inferred From

NDUFA10 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

XP_038430314.1, XP_038291894.1, XP_850303.3

ENSEMBL

ENSCAFT00845053825, ENSCAFP00845042304, ENSCAFG00845030335

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