Reactome | LOC612779 [nucleoplasm]

LOC612779 [nucleoplasm]

Stable Identifier

R-CFA-1214206

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

Me2K5-H3F3A, A0A8I3RQJ9

Locations in the PathwayBrowser

Expand all

Cell Cycle (Canis familiaris)

- Cell Cycle, Mitotic (Canis familiaris)
  - M Phase (Canis familiaris)
    - Mitotic Prophase (Canis familiaris)
      - Condensation of Prophase Chromosomes (Canis familiaris)
        
        CDK1 phosphorylates PHF8 (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        CDK1 phosphorylates condensin II subunit NCAPD3 (Canis familiaris)
        
        Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        Condensin II complex binds H4K20me1-containing nucleosomes (Canis familiaris)
        
        Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        PHF8 demethylates histone H4K20me1 (Canis familiaris)
        
        PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        PLK1 binds phosphorylated condensin II complex (Canis familiaris)
        
        Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        PLK1 hyperphosphorylates Condensin II complex (Canis familiaris)
        
        Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Canis familiaris)
        
        H3K4me2/3 [nucleoplasm] (Canis familiaris)
        
        H3K4me2 [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by Nuclear Receptors (Canis familiaris)
  - ESR-mediated signaling (Canis familiaris)
    - Estrogen-dependent gene expression (Canis familiaris)
      - Binding of AP1 transcriptional activator complexes to CCND1 promoter (Canis familiaris)
        
        CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] (Canis familiaris)
        
        CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
      - FOXA1 and GATA3 bind to CCND1 promoter (Canis familiaris)
        
        CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)
        
        CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Canis familiaris)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Canis familiaris)
        
        LOC612779 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3RQJ9

Gene Names

LOC612779

Reference Genes

BioGPS Gene:612779 LOC612779

ENSEMBL:ENSCAFG00845002237.1

KEGG:cfa:612779 LOC612779

Monarch:612779 LOC612779

NCBI Gene:612779 LOC612779

UCSC:A0A8I3RQJ9 LOC612779

Reference Transcript

Other Identifiers

612779

CfaAffx.2698.1.S1_s_at

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005694

GO:0030527

GO:0046982

Participates

as a candidate of

H3K4me2 [nucleoplasm] (Canis familiaris)

as a member of

Histone H3 (H3K4me2) [nucleoplasm] (Canis familiaris)

Other forms of this molecule

LOC612779 [nucleoplasm]

phospho-LOC612779 [nucleoplasm]

LOC612779 [nucleoplasm]

phospho-LOC612779 [nucleoplasm]

LOC612779 [nucleoplasm]

LOC612779 [extracellular region]

LOC612779 [nucleoplasm]

Inferred From

Me2K5-H3F3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6,N6-dimethyl-L-lysine at 5 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6-dimethyl-L-lysine [MOD:00084]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.

Cross References

RefSeq

XP_038509994.1, XP_038381864.1, XP_003432554.1

ENSEMBL

ENSCAFT00845003923, ENSCAFG00845002237, ENSCAFP00845003127

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