Reactome | PPBP [extracellular region]

PPBP [extracellular region]

Stable Identifier

R-CFA-114573

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

PPBP(35-128), A0A8I3NDZ2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Chemokine receptors bind chemokines (Canis familiaris)
        
        Receptor CXCR2 binds ligands CXCL1 to 7 (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Canis familiaris)
        
        CXCR2 ligands [extracellular region] (Canis familiaris)
        
        PPBP [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3NDZ2

Gene Names

PPBP

Reference Genes

BioGPS Gene:482196 PPBP

ENSEMBL:ENSCAFG00845006341.1

KEGG:cfa:482196 PPBP

Monarch:482196 PPBP

NCBI Gene:482196 PPBP

UCSC:A0A8I3NDZ2 PPBP

Reference Transcript

RefSeq:NM_001171772.3 PPBP

Other Identifiers

482196

Cfa.16778.1.S1_at

CfaAffx.5498.1.S1_s_at

GO:0002376

GO:0002523

GO:0005125

GO:0005576

GO:0005615

GO:0006935

GO:0006952

GO:0006954

GO:0006955

GO:0007165

GO:0008009

GO:0030593

GO:0042119

GO:0045236

GO:0048018

GO:0048870

GO:0061844

GO:0071222

GO:0098542

GO:0098772

Participates

as a member of

Other forms of this molecule

PPBP [tertiary granule lumen]

PPBP [extracellular region]

PPBP [platelet alpha granule lumen]

Inferred From

PPBP(35-128) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001165243.2

ENSEMBL

ENSCAFG00845006341, ENSCAFP00845008769, ENSCAFT00845011239