Reactome | lrch-1 [cytosol]

lrch-1 [cytosol]

Stable Identifier

R-CEL-976019

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

LRR1, Q17989

Locations in the PathwayBrowser

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Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Neddylation (Caenorhabditis elegans)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
        
        CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL2-box protein [cytosol] (Caenorhabditis elegans)
        
        lrch-1 [cytosol] (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL2-box protein [cytosol] (Caenorhabditis elegans)
        
        lrch-1 [cytosol] (Caenorhabditis elegans)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Caenorhabditis elegans)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL2-box protein [cytosol] (Caenorhabditis elegans)
        
        lrch-1 [cytosol] (Caenorhabditis elegans)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL2 E3 ligase complex [cytosol] (Caenorhabditis elegans)
        
        CUL2-box protein [cytosol] (Caenorhabditis elegans)
        
        lrch-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q17989

Gene Names

lrch-1

Reference Genes

BioGPS Gene:180893 lrch-1

CTD Gene:180893 lrch-1

ENSEMBL:WBGene00015779

KEGG:cel:CELE_C14F11.2 lrch-1

Monarch:180893 lrch-1

NCBI Gene:180893 lrch-1

UCSC:Q17989 lrch-1

Wormbase:WBGene00015779

Wormbase:WBGene00015779 lrch-1

Other Identifiers

180893

GO:0005515

GO:0035556

Participates

as a member of

CUL2-box protein [cytosol] (Caenorhabditis elegans)

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)

Inferred From

LRR1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_509042.1

ENSEMBL

C14F11.2.2, C14F11.2.1, C14F11.2.2, C14F11.2.1, WBGene00015779