Reactome | lin-35 [nucleoplasm]

lin-35 [nucleoplasm]

Stable Identifier

R-CEL-68642

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

RB1, G5EDT1

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Caenorhabditis elegans)

- Cellular responses to stress (Caenorhabditis elegans)
  - Cellular Senescence (Caenorhabditis elegans)
    - DNA Damage/Telomere Stress Induced Senescence (Caenorhabditis elegans)
      - Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Caenorhabditis elegans)
        
        SAHF formation (Caenorhabditis elegans)
        
        lin-35 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EDT1

Gene Names

lin-35

Reference Genes

BioGPS Gene:172249 lin-35

CTD Gene:172249 lin-35

ENSEMBL:WBGene00003020

KEGG:cel:CELE_C32F10.2 lin-35

Monarch:172249 lin-35

NCBI Gene:172249 lin-35

UCSC:G5EDT1 lin-35

Wormbase:WBGene00003020

Wormbase:WBGene00003020 lin-35

Reference Transcript

RefSeq:NM_059285.4 lin-35

Other Identifiers

172249

GO:0000785

GO:0000977

GO:0002119

GO:0003677

GO:0005515

GO:0005634

GO:0005667

GO:0006355

GO:0006357

GO:0008406

GO:0009792

GO:0010564

GO:0016479

GO:0019219

GO:0022414

GO:0030154

GO:0032876

GO:0035189

GO:0040018

GO:0040027

GO:0045930

GO:0048557

GO:0048856

GO:0051302

GO:0051726

GO:0060255

GO:0070176

GO:0090727

GO:1902806

GO:1902807

GO:2000134

Participates

as an input of

as a component of

as an output of

RB1 translocates to the nucleus (Caenorhabditis elegans)

This entity regulates

Positively

SAHF formation (Caenorhabditis elegans)

Other forms of this molecule

lin-35 [nucleoplasm]

phospho-lin-35 [nucleoplasm]

lin-35 [cytosol]

phospho-lin-35 [nucleoplasm]

Inferred From

RB1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_491686.1

ENSEMBL

C32F10.2.1, C32F10.2.1, WBGene00003020

PRO

G5EDT1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q22703	2	dpl-1 [nucleoplasm] (R-CEL-68652) dpl-1 [nucleoplasm] (R-CEL-1362225)	0.544	2

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