Reactome | phospho-lin-35 [nucleoplasm]

phospho-lin-35 [nucleoplasm]

Stable Identifier

R-CEL-9687336

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

p-S230-RB1, G5EDT1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:G5EDT1

Gene Names

lin-35

Reference Genes

BioGPS Gene:172249 lin-35

CTD Gene:172249 lin-35

ENSEMBL:WBGene00003020

KEGG Gene (Caenorhabditis elegans):CELE_C32F10.2 lin-35

Monarch:172249 lin-35

NCBI Gene:172249 lin-35

Wormbase:WBGene00003020

Reference Transcript

RefSeq:NM_059285.3 lin-35

Other Identifiers

172249

175838_at

18452313

188392_s_at

A_12_P105471

C32F10.2

C32F10.2_2174-2233_0.915_15_C

C32F10.2_2328-2387_0.922_12_B

C32F10.2_2670-2729_0.926_11_A

C32F10_2P01639

C32F10_2P02036

C32F10_2P02644

CE24823

CE_WBGene00003020_A

CE_WBGene00003020_B

CGZ0007154

GO:0000003

GO:0000278

GO:0000785

GO:0000977

GO:0002119

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005667

GO:0005694

GO:0006357

GO:0007049

GO:0008022

GO:0008150

GO:0008406

GO:0009058

GO:0009790

GO:0009792

GO:0016479

GO:0030154

GO:0032876

GO:0032991

GO:0034641

GO:0035189

GO:0040007

GO:0040018

GO:0040027

GO:0043226

GO:0043433

GO:0045930

GO:0048557

GO:0048856

GO:0051301

GO:0051302

GO:0051726

GO:0070176

GO:0090727

GO:1902806

GO:1902807

GO:1903507

GO:2000134

WBGene00003020

cea2.c.01096

Participates

as an input of

Association of Rb with Cyclin E:Cdk2 complexes (Caenorhabditis elegans)

as a component of

CCNE:p-T160-CDK2:hypophosphorylated RB1 [nucleoplasm] (Caenorhabditis elegans)

as an output of

Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Caenorhabditis elegans)

Other forms of this molecule

phospho-lin-35 [nucleoplasm]

lin-35 [nucleoplasm]

phospho-lin-35 [nucleoplasm]

lin-35 [cytosol]

phospho-lin-35 [nucleoplasm]

Inferred From

monophosphorylated RB1 [nucleoplasm] (Homo sapiens)

p-S230-RB1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 230 (in Homo sapiens)

Coordinate

230

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_491686.1

PRO

G5EDT1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q22703	2	dpl-1 [nucleoplasm] (R-CEL-68652) dpl-1 [nucleoplasm] (R-CEL-1362225)	0.544	2