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HGF(32-494) [extracellular region]
Stable Identifier
R-CEL-56497
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
extracellular region
Synonyms
P91823
Locations in the PathwayBrowser
Expand all
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Response to elevated platelet cytosolic Ca2+ (Caenorhabditis elegans)
Platelet degranulation (Caenorhabditis elegans)
Exocytosis of platelet alpha granule contents (Caenorhabditis elegans)
Platelet alpha granule contents [extracellular region] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
RAS GEFs [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by MET (Caenorhabditis elegans)
MET activates RAS signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
MET promotes cell motility (Caenorhabditis elegans)
MET activates PTK2 signaling (Caenorhabditis elegans)
MET phosphorylates PTK2 (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
SRC phosphorylates PTK2 (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
Negative regulation of MET activity (Caenorhabditis elegans)
CBL monoubiquitinates activated MET (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
CBL recruits CIN85:endophilin to ubiquitinated MET (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
EPS15 and HGS bind ubiquitinated MET (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
MET phosphorylates CBL (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Caenorhabditis elegans)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Caenorhabditis elegans)
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Caenorhabditis elegans)
HGF dimer [extracellular region] (Caenorhabditis elegans)
HGF(32-494) [extracellular region] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P91823
Reference Genes
BioGPS Gene:188711
CTD Gene:188711
ENSEMBL:WBGene00011909
KEGG:cel:CELE_T22A3.6
Monarch:188711
NCBI Gene:188711
UCSC:P91823
Wormbase:WBGene00011909
Wormbase:WBGene00011909
Reference Transcript
RefSeq:NM_060372.3
Other Identifiers
188711
Participates
as a component of
HGF dimer [extracellular region] (Caenorhabditis elegans)
Other forms of this molecule
MST1(19-483) [extracellular region]
MST1(484-711) [extracellular region]
pro-MST1 [extracellular region]
PLG(20-580) [extracellular region]
PLG(581-810) [extracellular region]
PLG(1-810) [extracellular region]
PLG(20-810) [platelet alpha granule lumen]
HGF(32-494) [platelet alpha granule lumen]
HGF(495-728) [platelet alpha granule lumen]
pro-HGF [extracellular region]
HGF(495-728) [extracellular region]
Inferred From
HGF(32-494) [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_492773.3
ENSEMBL
T22A3.6.1
,
T22A3.6.1
,
WBGene00011909
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