Reactome | gar-1 [plasma membrane]

gar-1 [plasma membrane]

Stable Identifier

R-CEL-390910-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

HRH4, Q18007

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (i) signalling events (Caenorhabditis elegans)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
      - The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
  - GPCR ligand binding (Caenorhabditis elegans)
    - Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
      - Amine ligand-binding receptors (Caenorhabditis elegans)
        
        Histamine receptors (Caenorhabditis elegans)
        
        HRH4 binds Hist (Caenorhabditis elegans)
        
        HRH4:Hist [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-1 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q18007

Gene Names

gar-1

Reference Genes

BioGPS Gene:180922 gar-1

CTD Gene:180922 gar-1

ENSEMBL:WBGene00001517

KEGG:cel:CELE_C15B12.5 gar-1

Monarch:180922 gar-1

NCBI Gene:180922 gar-1

UCSC:Q18007 gar-1

Wormbase:WBGene00001517

Wormbase:WBGene00001517 gar-1

Reference Transcript

Other Identifiers

180922

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007187

GO:0007197

GO:0007213

GO:0007268

GO:0007271

GO:0016020

GO:0016907

GO:0030425

GO:0045202

GO:0045211

Participates

as a member of

Homologues of HRH4 [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

gar-1 [clathrin-coated endocytic vesicle membrane]

gar-1 [plasma membrane]

Inferred From

HRH4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001024402.1, NP_001024401.1, NP_001024403.1

ENSEMBL

C15B12.5b.1, WBGene00001517, C15B12.5b.1

PRO

Q18007