Reactome | gar-2 [plasma membrane]

gar-2 [plasma membrane]

Stable Identifier

R-CEL-390693

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

CHRM4, Q09388

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (i) signalling events (Caenorhabditis elegans)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
      - The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
  - GPCR ligand binding (Caenorhabditis elegans)
    - Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
      - Amine ligand-binding receptors (Caenorhabditis elegans)
        
        Muscarinic acetylcholine receptors (Caenorhabditis elegans)
        
        CHRM2,4 bind acetylcholine (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Caenorhabditis elegans)
        
        CHRM2,CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
        
        CHRM4 binds CHRM4 antagonists (Caenorhabditis elegans)
        
        CHRM4:CHRM4 antagonists [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)
        
        gar-2 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q09388

Gene Names

gar-2

Reference Genes

BioGPS Gene:175893 gar-2

CTD Gene:175893 gar-2

ENSEMBL:WBGene00001518

KEGG:cel:CELE_F47D12.1 gar-2

Monarch:175893 gar-2

NCBI Gene:175893 gar-2

UCSC:Q09388 gar-2

Wormbase:WBGene00001518

Wormbase:WBGene00001518 gar-2

Reference Transcript

Other Identifiers

175893

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007187

GO:0007197

GO:0007213

GO:0007268

GO:0009410

GO:0016020

GO:0016907

GO:0030424

GO:0030425

GO:0032223

GO:0038023

GO:0042995

GO:0045202

Participates

as a member of

Homologues of CHRM4 [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

gar-2 [clathrin-coated endocytic vesicle membrane]

gar-2 [plasma membrane]

Inferred From

CHRM4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001022593.1, NP_001022594.1

ENSEMBL

F47D12.1a.1, F47D12.1a.1, WBGene00001518

PRO

Q09388

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