Reactome | rnp-4 [cytosol]

rnp-4 [cytosol]

Stable Identifier

R-CEL-162462

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RBM8A, Q21832

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
- Processing of Capped Intron-Containing Pre-mRNA (Caenorhabditis elegans)
  - Transport of Mature Transcript to Cytoplasm (Caenorhabditis elegans)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Caenorhabditis elegans)
      - mRNP complex dissociates from cytosolic face of NPC (Caenorhabditis elegans)
        
        NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Caenorhabditis elegans)
        
        EJC [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
        
        mRNA:CBC:EJC:POLDIP3 [cytosol] (Caenorhabditis elegans)
        
        EJC [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21832

Gene Names

rnp-4

Reference Genes

BioGPS Gene:175572 rnp-4

ENSEMBL:WBGene00004387

KEGG:cel:CELE_R07E5.14 rnp-4

Monarch:175572 rnp-4

NCBI Gene:175572 rnp-4

UCSC:Q21832 rnp-4

Wormbase:WBGene00004387

Wormbase:WBGene00004387 rnp-4

Reference Transcript

RefSeq:NM_001384072.2 rnp-4

Other Identifiers

175572

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005737

GO:0006396

GO:0006397

GO:0008380

GO:0016071

GO:0016607

GO:0030620

GO:0035145

GO:0036002

GO:0040022

GO:0048598

GO:0051028

GO:0071028

GO:1905881

Participates

as a component of

Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

rnp-4 [nucleoplasm]

Inferred From

RBM8A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001369846.1

ENSEMBL

R07E5.14.2, R07E5.14.2, R07E5.14.1, R07E5.14.1, WBGene00004387