Reactome | bub-1 [cytosol]

bub-1 [cytosol]

Stable Identifier

R-CEL-141436

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

BUB1B, Q21776

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - Mitotic Spindle Checkpoint (Caenorhabditis elegans)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        bub-1 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        bub-1 [cytosol] (Caenorhabditis elegans)
- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - Regulation of mitotic cell cycle (Caenorhabditis elegans)
    - APC/C-mediated degradation of cell cycle proteins (Caenorhabditis elegans)
      - Regulation of APC/C activators between G1/S and early anaphase (Caenorhabditis elegans)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        bub-1 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        bub-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21776

Gene Names

bub-1

Reference Genes

BioGPS Gene:172468 bub-1

CTD Gene:172468 bub-1

ENSEMBL:WBGene00000275

KEGG:cel:CELE_R06C7.8 bub-1

Monarch:172468 bub-1

NCBI Gene:172468 bub-1

UCSC:Q21776 bub-1

Wormbase:WBGene00000275

Wormbase:WBGene00000275 bub-1

Reference Transcript

RefSeq:NM_059650.8 bub-1

Other Identifiers

172468

GO:0000212

GO:0000280

GO:0000775

GO:0000776

GO:0000940

GO:0003824

GO:0004672

GO:0004674

GO:0004676

GO:0004677

GO:0004679

GO:0004694

GO:0004711

GO:0005515

GO:0005524

GO:0005634

GO:0005694

GO:0005737

GO:0005938

GO:0006325

GO:0006338

GO:0006468

GO:0007010

GO:0007094

GO:0008406

GO:0016740

GO:0022414

GO:0032991

GO:0034501

GO:0035175

GO:0035402

GO:0035403

GO:0035979

GO:0043226

GO:0043515

GO:0044022

GO:0044023

GO:0044024

GO:0044025

GO:0048598

GO:0048666

GO:0048856

GO:0051257

GO:0051301

GO:0051307

GO:0051316

GO:0051321

GO:0051754

GO:0072354

GO:0072371

GO:0072518

GO:0106310

GO:0110039

GO:0140096

GO:0140823

GO:0140855

GO:0140857

GO:1903394

GO:1905342

GO:1990244

GO:1990298

GO:1990299

Participates

as an input of

Formation of the MCC complex (Caenorhabditis elegans)

as a component of

hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)

Inferred From

BUB1B [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_492051.1

ENSEMBL

R06C7.8.1, R06C7.8.1, WBGene00000275

PRO

Q21776

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