Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
bub-1 [cytosol]
Stable Identifier
R-CEL-141436
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
BUB1B, Q21776
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle Checkpoints (Caenorhabditis elegans)
Mitotic Spindle Checkpoint (Caenorhabditis elegans)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
Formation of the MCC complex (Caenorhabditis elegans)
bub-1 [cytosol] (Caenorhabditis elegans)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
bub-1 [cytosol] (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Regulation of mitotic cell cycle (Caenorhabditis elegans)
APC/C-mediated degradation of cell cycle proteins (Caenorhabditis elegans)
Regulation of APC/C activators between G1/S and early anaphase (Caenorhabditis elegans)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
Formation of the MCC complex (Caenorhabditis elegans)
bub-1 [cytosol] (Caenorhabditis elegans)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
bub-1 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q21776
Gene Names
bub-1
Reference Genes
BioGPS Gene:172468 bub-1
CTD Gene:172468 bub-1
ENSEMBL:WBGene00000275
KEGG:cel:CELE_R06C7.8 bub-1
Monarch:172468 bub-1
NCBI Gene:172468 bub-1
UCSC:Q21776 bub-1
Wormbase:WBGene00000275
Wormbase:WBGene00000275 bub-1
Reference Transcript
RefSeq:NM_059650.8 bub-1
Other Identifiers
172468
GO:0000212
GO:0000280
GO:0000775
GO:0000776
GO:0000940
GO:0003824
GO:0004672
GO:0004674
GO:0004676
GO:0004677
GO:0004679
GO:0004694
GO:0004711
GO:0005515
GO:0005524
GO:0005634
GO:0005694
GO:0005737
GO:0005938
GO:0006325
GO:0006338
GO:0006468
GO:0007010
GO:0007094
GO:0008406
GO:0016740
GO:0022414
GO:0032991
GO:0034501
GO:0035175
GO:0035402
GO:0035403
GO:0035979
GO:0043226
GO:0043515
GO:0044022
GO:0044023
GO:0044024
GO:0044025
GO:0048598
GO:0048666
GO:0048856
GO:0051257
GO:0051301
GO:0051307
GO:0051316
GO:0051321
GO:0051754
GO:0072354
GO:0072371
GO:0072518
GO:0106310
GO:0110039
GO:0140096
GO:0140823
GO:0140855
GO:0140857
GO:1903394
GO:1905342
GO:1990244
GO:1990298
GO:1990299
Participates
as an input of
Formation of the MCC complex (Caenorhabditis elegans)
as a component of
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
Inferred From
BUB1B [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_492051.1
ENSEMBL
R06C7.8.1
,
R06C7.8.1
,
WBGene00000275
PRO
Q21776
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text