Reactome | san-1 [cytosol]

san-1 [cytosol]

Stable Identifier

R-CEL-141436

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

BUB1B, O02053

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - Mitotic Spindle Checkpoint (Caenorhabditis elegans)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        Homologues of BUB1B [cytosol] (Caenorhabditis elegans)
        
        san-1 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        Homologues of BUB1B [cytosol] (Caenorhabditis elegans)
        
        san-1 [cytosol] (Caenorhabditis elegans)
- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - Regulation of mitotic cell cycle (Caenorhabditis elegans)
    - APC/C-mediated degradation of cell cycle proteins (Caenorhabditis elegans)
      - Regulation of APC/C activators between G1/S and early anaphase (Caenorhabditis elegans)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        Homologues of BUB1B [cytosol] (Caenorhabditis elegans)
        
        san-1 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        Homologues of BUB1B [cytosol] (Caenorhabditis elegans)
        
        san-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O02053

Gene Names

san-1

Reference Genes

BioGPS Gene:172342 san-1

CTD Gene:172342 san-1

ENSEMBL:WBGene00004721

KEGG:cel:CELE_ZC328.4 san-1

Monarch:172342 san-1

NCBI Gene:172342 san-1

UCSC:O02053 san-1

Wormbase:WBGene00004721

Wormbase:WBGene00004721 san-1

Reference Transcript

RefSeq:NM_059445.7 san-1

Other Identifiers

172342

GO:0000776

GO:0003824

GO:0004672

GO:0005515

GO:0005634

GO:0005654

GO:0007094

GO:0016740

GO:0034059

GO:0043226

GO:0051726

GO:0051754

GO:0140096

Participates

as a member of

Homologues of BUB1B [cytosol] (Caenorhabditis elegans)

Inferred From

BUB1B [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_491846.2

ENSEMBL

WBGene00004721, ZC328.4.1, ZC328.4.1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9XWH0	1	bub-3 [cytosol] (R-CEL-141416)	0.621	5

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