Reactome | bub-3 [cytosol]

bub-3 [cytosol]

Stable Identifier

R-CEL-141416

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

BUB3, Q9XWH0

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - Mitotic Spindle Checkpoint (Caenorhabditis elegans)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)
- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - Regulation of mitotic cell cycle (Caenorhabditis elegans)
    - APC/C-mediated degradation of cell cycle proteins (Caenorhabditis elegans)
      - Regulation of APC/C activators between G1/S and early anaphase (Caenorhabditis elegans)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9XWH0

Gene Names

bub-3

Reference Genes

BioGPS Gene:175018 bub-3

ENSEMBL:WBGene00013209

KEGG Gene (Caenorhabditis elegans):CELE_Y54G9A.6 bub-3

Monarch:175018 bub-3

NCBI Gene:175018 bub-3

UCSC:Q9XWH0 bub-3

Wormbase:WBGene00013209

Reference Transcript

RefSeq:NM_064478.4 bub-3

Other Identifiers

172992_s_at

175018

18491331

192853_at

A_12_P108441

CE19233

CE_WBGene00013209_A

CE_WBGene00013209_B

CGZ0049276

GO:0000003

GO:0000278

GO:0000775

GO:0000776

GO:0000777

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0007049

GO:0007059

GO:0007094

GO:0008150

GO:0009790

GO:0009792

GO:0032182

GO:0032991

GO:0033316

GO:0033597

GO:0043130

GO:0043226

GO:0048856

GO:0051276

GO:0051301

GO:0051321

GO:0051726

GO:0140014

GO:1990298

WBGene00013209

Y54G9A.6

Y54G9A.6_711-770_0.954_2_B

Y54G9A.6_815-874_0.948_4_C

Y54G9A.6_910-969_0.958_1_A

Y54G9A_6P00107

Y54G9A_6P00363

Y54G9A_6P00905

cea2.c.15540

Participant Of

input

Formation of the MCC complex

hasComponent

hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol]

Inferred From

BUB3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_496879.1

PRO

Q9XWH0

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O02053	1	san-1 [cytosol] (R-CEL-141436)	0.621	5

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