Reactome | bub-3 [cytosol]

bub-3 [cytosol]

Stable Identifier

R-CEL-141416

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

BUB3, Q9XWH0

Locations in the PathwayBrowser

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Cell Cycle (Caenorhabditis elegans)

- Cell Cycle Checkpoints (Caenorhabditis elegans)
  - Mitotic Spindle Checkpoint (Caenorhabditis elegans)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)
- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - Regulation of mitotic cell cycle (Caenorhabditis elegans)
    - APC/C-mediated degradation of cell cycle proteins (Caenorhabditis elegans)
      - Regulation of APC/C activators between G1/S and early anaphase (Caenorhabditis elegans)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Caenorhabditis elegans)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Caenorhabditis elegans)
        
        Formation of the MCC complex (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)
        
        bub-3 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9XWH0

Gene Names

bub-3

Reference Genes

BioGPS Gene:175018 bub-3

ENSEMBL:WBGene00013209

KEGG:cel:CELE_Y54G9A.6 bub-3

Monarch:175018 bub-3

NCBI Gene:175018 bub-3

UCSC:Q9XWH0 bub-3

Wormbase:WBGene00013209

Wormbase:WBGene00013209 bub-3

Reference Transcript

RefSeq:NM_064478.7 bub-3

Other Identifiers

175018

GO:0000775

GO:0000776

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0007094

GO:0009792

GO:0022414

GO:0033316

GO:0033597

GO:0043130

GO:0043226

GO:0048856

GO:0051301

GO:0051321

GO:0051726

GO:1990298

GO:1990299

Participates

as an input of

Formation of the MCC complex (Caenorhabditis elegans)

as a component of

hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Caenorhabditis elegans)

Inferred From

BUB3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_496879.1

ENSEMBL

WBGene00013209, Y54G9A.6.1, Y54G9A.6.1

PRO

Q9XWH0

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O02053 O02053			0.621	5

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