Reactome | cle-1 [extracellular region]

cle-1 [extracellular region]

Stable Identifier

R-CEL-139938

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

COL4A3(29-1670), G5EGA4

Locations in the PathwayBrowser

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Developmental Biology (Caenorhabditis elegans)

- Nervous system development (Caenorhabditis elegans)
  - Axon guidance (Caenorhabditis elegans)
    - NCAM signaling for neurite out-growth (Caenorhabditis elegans)
      - NCAM1 interactions (Caenorhabditis elegans)
        
        Interaction of NCAM1 with collagens (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-3(IV):Collagen alpha-4(IV):Collagen alpha-5(IV) triple helix [extracellular region] (Caenorhabditis elegans)
        
        cle-1 [extracellular region] (Caenorhabditis elegans)
        
        NCAM-1:Collagen complex [plasma membrane] (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-3(IV):Collagen alpha-4(IV):Collagen alpha-5(IV) triple helix [extracellular region] (Caenorhabditis elegans)
        
        cle-1 [extracellular region] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
  - Signaling by PDGF (Caenorhabditis elegans)
    - PDGF binds to extracellular matrix proteins (Caenorhabditis elegans)
      - Extracellular matrix ligands [extracellular region] (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-3(IV):Collagen alpha-4(IV):Collagen alpha-5(IV) triple helix [extracellular region] (Caenorhabditis elegans)
        
        cle-1 [extracellular region] (Caenorhabditis elegans)
      - PDGF A and B chains:ECM complex [extracellular region] (Caenorhabditis elegans)
        
        Extracellular matrix ligands [extracellular region] (Caenorhabditis elegans)
        
        Collagens [extracellular region] (Caenorhabditis elegans)
        
        Collagen alpha-3(IV):Collagen alpha-4(IV):Collagen alpha-5(IV) triple helix [extracellular region] (Caenorhabditis elegans)
        
        cle-1 [extracellular region] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EGA4

Gene Names

cle-1

Reference Genes

BioGPS Gene:172678 cle-1

CTD Gene:172678 cle-1

ENSEMBL:WBGene00000527

KEGG:cel:CELE_C36B1.1 cle-1

Monarch:172678 cle-1

NCBI Gene:172678 cle-1

UCSC:G5EGA4 cle-1

Wormbase:WBGene00000527

Wormbase:WBGene00000527 cle-1

Reference Transcript

RefSeq:NM_059957.3 cle-1

Other Identifiers

172678

GO:0001764

GO:0005198

GO:0005515

GO:0005576

GO:0005581

GO:0005587

GO:0005604

GO:0007271

GO:0007411

GO:0030020

GO:0030054

GO:0030312

GO:0031012

GO:0034330

GO:0035418

GO:0040039

GO:0045202

GO:0048870

GO:0050808

Participates

as a component of

Collagen alpha-3(IV):Collagen alpha-4(IV):Collagen alpha-5(IV) triple helix [extracellular region] (Caenorhabditis elegans)

Other forms of this molecule

cle-1 [endoplasmic reticulum lumen]

cle-1 [extracellular region]

Inferred From

COL4A3(29-1670) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_492358.3

ENSEMBL

WBGene00000527, C36B1.1d.1, C36B1.1d.1

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P30632 ASNA			0.488	2
UniProt:Q21746	1	sgt-1 [cytosol] (R-CEL-5423595)	0.488	2

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