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FBXL12 [cytosol]
Stable Identifier
R-BTA-8862611
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
FBXL12, Q32PG9
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen processing: Ubiquitination & Proteasome degradation (Bos taurus)
Interaction of E3 with substrate and E2-Ub complex (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
Polyubiquitination of substrate (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
Release of E3 from polyubiquitinated substrate (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Neddylation (Bos taurus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Bos taurus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Bos taurus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligases [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligases [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligases [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Bos taurus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
SCF E3 ubiquitin ligase [cytosol] (Bos taurus)
F-box protein [cytosol] (Bos taurus)
FBXL12 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q32PG9
Gene Names
FBXL12
Reference Genes
BioGPS Gene:617304 FBXL12
ENSEMBL:ENSBTAG00000025148
KEGG:bta:617304 FBXL12
Monarch:617304 FBXL12
NCBI Gene:617304 FBXL12
UCSC:Q32PG9 FBXL12
Reference Transcript
RefSeq:NM_001040600.2 FBXL12
Other Identifiers
617304
Bt.25652.1.A1_at
GO:0005515
Participates
as a member of
F-box protein [cytosol] (Bos taurus)
Inferred From
FBXL12 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001035690.1
ENSEMBL
ENSBTAT00000035207
,
ENSBTAG00000025148
,
ENSBTAP00000035085
VGNC
52772
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