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MARK3 [cytosol]
Stable Identifier
R-BTA-5672591
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
A0A3Q1LWF1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
MITF-M-regulated melanocyte development (Bos taurus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Bos taurus)
MARK3 phosphorylates MITF-M on S173 (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
Dissociation of RAS:RAF complex (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Negative regulation of MAPK pathway (Bos taurus)
BRAP binds KSR1:MARK3 (Bos taurus)
BRAP:KSR1:MARK3 [cytosol] (Bos taurus)
KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
PP2A dephosphorylates KSR1 (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Phosphorylation of RAF (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
activated RAF/KSR1 [plasma membrane] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Bos taurus)
BRAP:KSR1:MARK3 [cytosol] (Bos taurus)
KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
Raf dimer inhibitors bind RAF heterodimers (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
dephosphorylated "receiver" RAF/KSR1 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
YWHAB dimer dissociates from KSR1:MARK3 (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Bos taurus)
p-S311,S406 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Bos taurus)
p-S311,S406 KSR1:MARK3 [cytosol] (Bos taurus)
MARK3 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1LWF1
Reference Genes
BioGPS Gene:534872
ENSEMBL:ENSBTAG00000013410.6
KEGG:bta:534872
Monarch:534872
NCBI Gene:534872
UCSC:A0A3Q1LWF1
Reference Transcript
RefSeq:XM_024982187.2
Other Identifiers
534872
Bt.26941.1.A1_at
Bt.26941.2.S1_a_at
GO:0000166
GO:0000226
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005737
GO:0005886
GO:0006468
GO:0007010
GO:0010389
GO:0016301
GO:0016740
GO:0019903
GO:0030425
GO:0035331
GO:0035556
GO:0042995
GO:0050321
GO:0106310
GO:0140096
GO:1900181
Participates
as a component of
p-S311,S406 KSR1:MARK3 [cytosol] (Bos taurus)
KSR1:MARK3 [cytosol] (Bos taurus)
p-S311 KSR1:MARK3 [cytosol] (Bos taurus)
p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)
Inferred From
MARK3 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAG00000013410
,
ENSBTAT00000074266
,
ENSBTAP00000061748
VGNC
31249
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