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GNAI2 [plasma membrane]
Stable Identifier
R-BTA-55435
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
A7MBH9
Locations in the PathwayBrowser
Expand all
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Activated P2Y purinoceptor 12 binds G-protein Gi (Bos taurus)
ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Dissociation of the P2Y purinoceptor 12:Gi complex (Bos taurus)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Gi activation by P2Y purinoceptor 12 (Bos taurus)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GDP [plasma membrane] (Bos taurus)
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Gi,Go Heterotrimeric G-protein complex dissociates (Bos taurus)
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
GABA receptor activation (Bos taurus)
GABA B receptor activation (Bos taurus)
Activation of GABAB receptors (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Dissociation of the Gi alpha:G olf complex (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha (i):GTP:RGS [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha (i):GTP:RGS [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha (i):GTP:SRC-1 [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Inactive G alpha (i) reassociates with G beta:gamma (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Opioid Signalling (Bos taurus)
G-protein mediated events (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Dissociation of the Gi alpha:G olf complex (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
G-proteins dissociate from plasma-membrane estrogen receptors (Bos taurus)
ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Bos taurus)
ESTG:ESRs:STRN:heterotrimeric G(i) protein [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
Membrane estrogen receptors bind SRC (Bos taurus)
G-protein alpha (i):GDP [plasma membrane] (Bos taurus)
G alpha (i) [plasma membrane] (Bos taurus)
GNAI2 [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:A7MBH9
Reference Genes
BioGPS Gene:281791
ENSEMBL:ENSBTAG00000020645.6
KEGG:bta:281791
Monarch:281791
NCBI Gene:281791
UCSC:A7MBH9
Reference Transcript
RefSeq:NM_001101040.1
Participates
as a candidate of
G alpha (i,o) (candidates) [plasma membrane] (Bos taurus)
as a member of
G alpha (i) [plasma membrane] (Bos taurus)
Inferred From
GNAI2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001094510.1
VGNC
29450
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