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phospho-SPHK1 [cytosol]
Stable Identifier
R-BTA-5218716
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
p-S225-SPHK1, F1MXZ6
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antimicrobial mechanism of IFN-stimulated genes (Bos taurus)
PKR-mediated signaling (Bos taurus)
SPHK1 binds PKR (Bos taurus)
EIF2AK2:p-SPHK1 [cytosol] (Bos taurus)
phospho-SPHK1 [cytosol] (Bos taurus)
phospho-SPHK1 [cytosol] (Bos taurus)
p-S225-SPHK1 localizes to cytosol (Bos taurus)
phospho-SPHK1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated cell proliferation (Bos taurus)
PKC phosphorylates sphingosine kinase 1 (Bos taurus)
phospho-SPHK1 [cytosol] (Bos taurus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)
phospho-SPHK1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MXZ6
Gene Names
SPHK1
Reference Genes
ENSEMBL:ENSBTAG00000008507.5
UCSC:F1MXZ6 SPHK1
Other Identifiers
618605
Bt.12438.1.S1_at
Bt.7037.1.S1_at
GO:0000287
GO:0001568
GO:0003677
GO:0005516
GO:0005524
GO:0005634
GO:0005737
GO:0005886
GO:0005905
GO:0005929
GO:0006629
GO:0006670
GO:0006954
GO:0007420
GO:0008283
GO:0008284
GO:0008289
GO:0008481
GO:0010803
GO:0016301
GO:0016407
GO:0016740
GO:0017050
GO:0019722
GO:0030100
GO:0030139
GO:0030307
GO:0030335
GO:0031398
GO:0031410
GO:0031901
GO:0032651
GO:0034612
GO:0035924
GO:0038036
GO:0043066
GO:0043226
GO:0045766
GO:0045840
GO:0045931
GO:0045987
GO:0046512
GO:0048146
GO:0048856
GO:0050764
GO:0051721
GO:0070301
GO:0071897
GO:0090520
GO:0098793
GO:0150077
GO:1900060
GO:1900745
GO:1901224
GO:1903978
GO:1905364
Participates
as an input of
SPHK1 binds PKR (Bos taurus)
as an output of
PKC phosphorylates sphingosine kinase 1 (Bos taurus)
p-S225-SPHK1 localizes to cytosol (Bos taurus)
as a component of
EIF2AK2:p-SPHK1 [cytosol] (Bos taurus)
Other forms of this molecule
SPHK1 [cytosol]
SPHK1 [nucleoplasm]
phospho-SPHK1 [nucleoplasm]
Inferred From
p-S225-SPHK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 225 (in Homo sapiens)
Coordinate
225
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ENSEMBL
ENSBTAP00000011212
,
ENSBTAT00000011212
,
ENSBTAG00000008507
VGNC
35210
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