Reactome | PARP1 [nucleoplasm]

PARP1 [nucleoplasm]

Stable Identifier

R-BTA-4551617

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

polySUMO2,3-K203,K486-PARP1, A0A3Q1MVZ1

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - SUMOylation (Bos taurus)
    - SUMO E3 ligases SUMOylate target proteins (Bos taurus)
      - SUMOylation of DNA damage response and repair proteins (Bos taurus)
        
        PIAS4 SUMOylates PARP1 with SUMO2,3 (Bos taurus)
        
        PARP1 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1MVZ1

Gene Names

PARP1

Reference Genes

ENSEMBL:ENSBTAG00000000837.5

UCSC:A0A3Q1MVZ1 PARP1

Other Identifiers

286764

Bt.4803.1.S1_at

GO:0000122

GO:0000724

GO:0000785

GO:0003677

GO:0003682

GO:0003684

GO:0003824

GO:0003950

GO:0005634

GO:0005635

GO:0005654

GO:0005667

GO:0005730

GO:0005739

GO:0005829

GO:0006281

GO:0006302

GO:0006310

GO:0006325

GO:0006355

GO:0006915

GO:0006974

GO:0007005

GO:0008047

GO:0008270

GO:0016604

GO:0016740

GO:0019899

GO:0019901

GO:0030592

GO:0031491

GO:0032042

GO:0032786

GO:0032869

GO:0032880

GO:0032991

GO:0032993

GO:0034244

GO:0034599

GO:0034644

GO:0035861

GO:0042802

GO:0042803

GO:0043123

GO:0043504

GO:0043596

GO:0045824

GO:0045944

GO:0051287

GO:0055086

GO:0061629

GO:0070212

GO:0070213

GO:0071168

GO:0071932

GO:0090734

GO:0098772

GO:0140096

GO:0140294

GO:0140805

GO:0140806

GO:0140807

GO:0140808

GO:0140815

GO:0140816

GO:0140817

GO:0140861

GO:0160049

GO:0160239

GO:1901135

GO:1905051

GO:1905168

GO:1990166

GO:1990404

GO:1990966

GO:2001170

Participates

as an output of

PIAS4 SUMOylates PARP1 with SUMO2,3 (Bos taurus)

Other forms of this molecule

PARP1 [nucleoplasm]

Inferred From

polySUMO2,3-K203,K486-PARP1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 203 (in Homo sapiens)

Coordinate

203

Modification

polySUMO2,3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 486 (in Homo sapiens)

Coordinate

486

Modification

polySUMO2,3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

ENSEMBL

ENSBTAT00000080992, ENSBTAG00000000837, ENSBTAP00000059409

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