Reactome | MAPK9 [cytosol]

MAPK9 [cytosol]

Stable Identifier

R-BTA-450355

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

MAPK9, A0A3Q1LJU7

Locations in the PathwayBrowser

Expand all

Immune System (Bos taurus)

- Cytokine Signaling in Immune system (Bos taurus)
  - Signaling by Interleukins (Bos taurus)
    - Interleukin-17 signaling (Bos taurus)
      - MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
- Innate Immune System (Bos taurus)
  - Fc epsilon receptor (FCERI) signaling (Bos taurus)
    - FCERI mediated MAPK activation (Bos taurus)
      - Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
  - Toll-like Receptor Cascades (Bos taurus)
    - Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
      - MyD88 cascade initiated on plasma membrane (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
    - Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
      - Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
      - Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
    - Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
      - MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
    - Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
      - MyD88-independent TLR4 cascade (Bos taurus)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
    - Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
      - MyD88 cascade initiated on plasma membrane (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
      - MyD88 dependent cascade initiated on endosome (Bos taurus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)
    - Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
      - MyD88 dependent cascade initiated on endosome (Bos taurus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
        
        MAP kinase activation (Bos taurus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
        
        MAPK8,9,10 [cytosol] (Bos taurus)
        
        MAPK9 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1LJU7

Gene Names

MAPK9

Reference Genes

BioGPS Gene:534125 MAPK9

ENSEMBL:ENSBTAG00000004709.6

Monarch:534125 MAPK9

NCBI Gene:534125 MAPK9

UCSC:A0A3Q1LJU7 MAPK9

Reference Transcript

RefSeq:XM_005208371.5 MAPK9

Other Identifiers

534125

Bt.22193.1.A1_at

Bt.22193.2.S1_at

GO:0000165

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0004705

GO:0004707

GO:0004712

GO:0005524

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0005886

GO:0006468

GO:0006954

GO:0007254

GO:0010628

GO:0010744

GO:0016301

GO:0016607

GO:0016740

GO:0031398

GO:0032436

GO:0034614

GO:0042752

GO:0043488

GO:0046686

GO:0048511

GO:0050804

GO:0061157

GO:0061833

GO:0071803

GO:0090594

GO:0097190

GO:0098685

GO:0106310

GO:0140096

GO:1900017

GO:2001235

Participates

as a member of

MAPK8,9,10 [cytosol] (Bos taurus)

Other forms of this molecule

phospho-MAPK9 [cytosol]

phospho-MAPK9 [nucleoplasm]

Inferred From

MAPK9 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSBTAP00000056751, ENSBTAG00000004709, ENSBTAT00000082454

VGNC

31227

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