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RIPK3 [cytosol]
Stable Identifier
R-BTA-450328
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
E1BKA8
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
IKK complex recruitment mediated by RIP1 (Bos taurus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
TRIF-mediated programmed cell death (Bos taurus)
RIP3 binds TRIF to mediate necroptosis (Bos taurus)
RIP3:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
RIP3:RIP1:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIP3:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
Programmed Cell Death (Bos taurus)
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
RIPK1 is phosphorylated (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
p-S-RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3 is phosphorylated (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
p-S-RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
Regulation of necroptotic cell death (Bos taurus)
O-GlcNAcylation of RIPK3 (TLR4 signaling) (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
PRKN polyubiquitinates RIPK3 (Bos taurus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3 binds HSP90:CDC37 (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3:HSP90:CDC37 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3 binds STUB1 (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3:STUB1 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3 binds p-S9-PRKN (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK3 is cleaved by CASP8 (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
STUB1 ubiquitinates RIPK3 at K55, K363 (Bos taurus)
RIPK3:STUB1 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
Small molecule inhibitor binds RIPK1, RIPK3 (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK3 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BKA8
Reference Genes
ENSEMBL:ENSBTAG00000018422.6
UCSC:E1BKA8
Participates
as an input of
RIPK3 binds HSP90:CDC37 (Bos taurus)
RIPK3 binds p-S9-PRKN (Bos taurus)
RIPK3 binds STUB1 (Bos taurus)
O-GlcNAcylation of RIPK3 (TLR4 signaling) (Bos taurus)
RIPK3 is cleaved by CASP8 (Bos taurus)
RIP3 binds TRIF to mediate necroptosis (Bos taurus)
as a component of
RIPK3:HSP90:CDC37 [cytosol] (Bos taurus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Bos taurus)
RIPK3:STUB1 [cytosol] (Bos taurus)
p-S-RIPK1:RIPK3 [cytosol] (Bos taurus)
RIPK1:RIPK3 [cytosol] (Bos taurus)
RIP3:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
RIP3:RIP1:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
This entity regulates
Negatively
TRIF:activated TLR3/TLR4 complex recruits RIP1
(Bos taurus)
Other forms of this molecule
phospho-p-S199,227, K48pUb-363-RIPK3 [cytosol]
K33polyUb-K197,302,364-RIPK3 [cytosol]
OGlcNAc-T467-RIPK3 [cytosol]
RIPK3(329-518) [cytosol]
RIPK3(1-328) [cytosol]
Ub-K55,363-RIPK3 [cytosol]
phospho-p-S199,227-RIPK3 [cytosol]
Inferred From
RIPK3 [cytosol]
(Homo sapiens)
Cross References
VGNC
52818
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