Reactome | IL1RAP [plasma membrane]

IL1RAP [plasma membrane]

Stable Identifier

R-BTA-445745

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

IL1RAP-1, A0A3Q1MKU4

Locations in the PathwayBrowser

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Signal Transduction (Bos taurus)

- Intracellular signaling by second messengers (Bos taurus)
  - PIP3 activates AKT signaling (Bos taurus)
    - Negative regulation of the PI3K/AKT network (Bos taurus)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
        
        PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Bos taurus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Bos taurus)
        
        IL33:IL1RL1:IL1RAP-1 [plasma membrane] (Bos taurus)
        
        IL1RAP [plasma membrane] (Bos taurus)
    - PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
      - IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Bos taurus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Bos taurus)
        
        IL33:IL1RL1:IL1RAP-1 [plasma membrane] (Bos taurus)
        
        IL1RAP [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1MKU4

Gene Names

IL1RAP

Reference Genes

ENSEMBL:ENSBTAG00000013205.6

UCSC:A0A3Q1MKU4 IL1RAP

Other Identifiers

539334

Bt.28708.1.S1_at

GO:0002114

GO:0004908

GO:0007165

GO:0015026

GO:0019221

GO:0032736

GO:0032753

GO:0032754

GO:0032755

GO:0038172

GO:0045202

GO:0051965

GO:0070498

GO:0098978

GO:0099151

GO:0099545

GO:0099560

GO:1905606

Participates

as an input of

as a component of

Inferred From

IL1RAP-1 [plasma membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSBTAP00000071554, ENSBTAT00000070445, ENSBTAG00000013205

VGNC

30133

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