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PIK3R5 [cytosol]
Stable Identifier
R-BTA-392289
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
PIK3R5, E1BCV1
Locations in the PathwayBrowser
Expand all
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
GPVI stimulates PI3K beta, gamma (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Bos taurus)
PI3K alpha, beta, gamma [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Regulation of T cell activation by CD28 family (Bos taurus)
Co-stimulation by CD28 (Bos taurus)
CD28 dependent PI3K/Akt signaling (Bos taurus)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
CD28:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K binds CD28 (Bos taurus)
CD28:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Co-stimulation by ICOS (Bos taurus)
PI3K binds ICOS (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
ICOS:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Phospholipid metabolism (Bos taurus)
PI Metabolism (Bos taurus)
Synthesis of PIPs at the plasma membrane (Bos taurus)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Bos taurus)
PIK3C(1) [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)
PIK3(2) [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
CD28:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
ICOS:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
CD28:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
ICOS:PI3K [plasma membrane] (Bos taurus)
Class 1A PI3Ks [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Signaling by Erythropoietin (Bos taurus)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Bos taurus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K bound to EPOR [plasma membrane] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:PI3K [plasma membrane] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] (Bos taurus)
PI3K alpha, gamma [cytosol] (Bos taurus)
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G-protein beta:gamma signalling (Bos taurus)
G beta:gamma signalling through PI3Kgamma (Bos taurus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Bos taurus)
G-protein beta-gamma:PI3K gamma [plasma membrane] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
Gbeta:gamma recruits PI3K gamma (Bos taurus)
G-protein beta-gamma:PI3K gamma [plasma membrane] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
PI3K gamma [cytosol] (Bos taurus)
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
PIK3R5 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BCV1
Gene Names
PIK3R5
Reference Genes
ENSEMBL:ENSBTAG00000005978.6
UCSC:E1BCV1 PIK3R5
Other Identifiers
614838
Bt.24675.1.S1_at
GO:0005829
GO:0005944
GO:0034451
GO:0046935
Participates
as a component of
PIK3CG:PIK3R5 [cytosol] (Bos taurus)
as a member of
PI3-kinase gamma, regulatory subunit [cytosol] (Bos taurus)
Inferred From
PIK3R5 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAP00000007845
,
ENSBTAT00000007845
,
ENSBTAG00000005978
VGNC
32896
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