Reactome | CEP78 [cytosol]

CEP78 [cytosol]

Stable Identifier

R-BTA-380304

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

CEP78, E1BK91

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Bos taurus)

- Cilium Assembly (Bos taurus)
  - Assembly of the 9+0 primary cilium (Bos taurus)
    - Anchoring of the basal body to the plasma membrane (Bos taurus)
      - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - C2CD3 binds the mother centriole (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)
        
        basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
        
        basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - CP110 and CEP97 dissociate from the centriole (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - MARK4 binds ODF2 in the centriole (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
        
        basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - Recruitment of transition zone proteins (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        basal body:transition zone proteins [cytosol] (Bos taurus)
        
        basal body [cytosol] (Bos taurus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
      - The distal appendage proteins recruit TTBK2 (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Bos taurus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Bos taurus)
        
        mother centriole:C2CD3 [cytosol] (Bos taurus)
        
        mother centriole [cytosol] (Bos taurus)
        
        CEP78 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BK91

Gene Names

CEP78

Reference Genes

ENSEMBL:ENSBTAG00000020752.6

UCSC:E1BK91 CEP78

Other Identifiers

537926

Bt.24231.1.A1_at

Bt.24231.2.S1_at

GO:0005515

GO:0005813

GO:0005814

GO:0005815

GO:0007018

GO:0022414

GO:0030317

GO:0031397

GO:0036064

GO:0043226

GO:0044782

GO:0048870

GO:0061512

GO:0071539

Participates

as a component of

Inferred From

CEP78 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSBTAT00000036653, ENSBTAG00000020752, ENSBTAP00000036509

VGNC

27214

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