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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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APBB1IP [cytosol]
Stable Identifier
R-BTA-354081
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
APBB1IP, Q3MHM0
Locations in the PathwayBrowser
Expand all
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activated integrin alphaIIb beta3 binds SHC1 (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Activation of Talin (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Autophosphorylation of PTK2 at Y397 (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Autophosphorylation of SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Clustering of Integrin alphaIIb beta3 complexes (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Dephosphorylation of inactive SRC by PTPB1 (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3 activation (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Release of CSK from SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SHC1 dissociates from integrin alphaIIb beta3 (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SYK activation by SRC (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SYK binds to integrin alphaIIb beta3 (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Translocation of PTK2 to Focal complexes (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Translocation of RIAM to plasma membrane (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Integrin signaling (Bos taurus)
Activated integrin alphaIIb beta3 binds SHC1 (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Activation of Talin (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Autophosphorylation of PTK2 at Y397 (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Autophosphorylation of SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Clustering of Integrin alphaIIb beta3 complexes (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Dephosphorylation of inactive SRC by PTPB1 (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3 activation (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Release of CSK from SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SHC1 dissociates from integrin alphaIIb beta3 (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SYK activation by SRC (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
SYK binds to integrin alphaIIb beta3 (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Translocation of PTK2 to Focal complexes (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Translocation of RIAM to plasma membrane (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
Dissociation of RAS:RAF complex (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
MAP2Ks and MAPKs bind to the activated RAF complex (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
RAF/MAPK scaffolds [cytosol] (Bos taurus)
Focal Adhesion/Focal contacts [plasma membrane] (Bos taurus)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
APBB1IP [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q3MHM0
Gene Names
APBB1IP
Reference Genes
BioGPS Gene:533670 APBB1IP
ENSEMBL:ENSBTAG00000012526.4
KEGG:bta:533670 APBB1IP
Monarch:533670 APBB1IP
NCBI Gene:533670 APBB1IP
UCSC:Q3MHM0 APBB1IP
Reference Transcript
RefSeq:XM_015473992.3 APBB1IP
RefSeq:NM_001034593.2 APBB1IP
RefSeq:XM_059892684.1 APBB1IP
RefSeq:XM_015473991.3 APBB1IP
Other Identifiers
533670
Bt.9211.1.S1_at
GO:0007165
Participates
as an input of
Translocation of RIAM to plasma membrane (Bos taurus)
as a component of
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
Inferred From
APBB1IP [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAG00000012526
,
ENSBTAT00000016629
,
ENSBTAP00000016629
VGNC
26004
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