Reactome | COP1 [nucleoplasm]

COP1 [nucleoplasm]

Stable Identifier

R-BTA-349454

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

RFWD2, F1MHX1

Locations in the PathwayBrowser

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Cell Cycle (Bos taurus)

- Cell Cycle Checkpoints (Bos taurus)
  - G1/S DNA Damage Checkpoints (Bos taurus)
    - p53-Dependent G1/S DNA damage checkpoint (Bos taurus)
      - p53-Dependent G1 DNA Damage Response (Bos taurus)
        
        Stabilization of p53 (Bos taurus)
        
        Autodegradation of the E3 ubiquitin ligase COP1 (Bos taurus)
        
        Phosphorylation of COP1 at Ser-387 by ATM (Bos taurus)
        
        COP1 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:F1MHX1

Gene Names

COP1

Reference Genes

ENSEMBL:ENSBTAG00000031385.4

Other Identifiers

519896

GO:0003824

GO:0005515

GO:0016740

GO:0030163

GO:0043161

GO:0046872

GO:0061630

GO:0140096

Participates

as a member of

DCAF protein [nucleoplasm] (Bos taurus)

as an input of

Phosphorylation of COP1 at Ser-387 by ATM (Bos taurus)

Other forms of this molecule

phospho-COP1 [cytosol]

phospho-COP1 [nucleoplasm]

Inferred From

RFWD2 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000143207

Ensembl

ENSBTAG00000031385, ENSBTAP00000041946, ENSBTAT00000044452

VGNC

50041