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FRS2 [cytosol]
Stable Identifier
R-BTA-190244
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
FRS2, E1B7I9
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
Frs2-mediated activation (Bos taurus)
FRS2 binds to active TrkA receptor (Bos taurus)
Active TrkA receptor:FRS2 complex [endosome membrane] (Bos taurus)
FRS2 [cytosol] (Bos taurus)
FRS2 [cytosol] (Bos taurus)
FRS2 is phosphorylated by active TrkA receptor (Bos taurus)
Active TrkA receptor:FRS2 complex [endosome membrane] (Bos taurus)
FRS2 [cytosol] (Bos taurus)
Signaling by NTRK2 (TRKB) (Bos taurus)
Activated NTRK2 signals through FRS2 and FRS3 (Bos taurus)
Activated NTRK2 binds FRS2 (Bos taurus)
BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Bos taurus)
FRS2 [cytosol] (Bos taurus)
FRS2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1B7I9
Gene Names
FRS2
Reference Genes
BioGPS Gene:538624 FRS2
ENSEMBL:ENSBTAG00000019155.4
ENSEMBL:ENSBTAG00000019155.5 FRS2
KEGG Gene (Bos taurus):538624 FRS2
Monarch:538624 FRS2
NCBI Gene:538624 FRS2
Reference Transcript
RefSeq:XM_010805102.2 FRS2
RefSeq:XM_010827723.2 FRS2
RefSeq:XM_581582.8 FRS2
RefSeq:XM_010805103.2 FRS2
RefSeq:XM_010827722.2 FRS2
RefSeq:XM_002687385.5 FRS2
Other Identifiers
538624
GO:0001702
GO:0001759
GO:0002088
GO:0003281
GO:0005068
GO:0005104
GO:0005168
GO:0005737
GO:0005886
GO:0005911
GO:0005912
GO:0007169
GO:0007405
GO:0008543
GO:0008595
GO:0012501
GO:0016020
GO:0022414
GO:0023052
GO:0030154
GO:0030900
GO:0042981
GO:0043410
GO:0046619
GO:0048856
GO:0050678
GO:0060090
GO:0060527
GO:0070307
GO:0070372
GO:2000726
Participates
as an input of
Activated NTRK2 binds FRS2 (Bos taurus)
FRS2 binds to active TrkA receptor (Bos taurus)
as a component of
BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Bos taurus)
Active TrkA receptor:FRS2 complex [endosome membrane] (Bos taurus)
Other forms of this molecule
phospho-FRS2 [cytosol]
phospho-FRS2 [cytosol]
phospho-FRS2 [plasma membrane]
FRS2 [plasma membrane]
phospho-FRS2 [plasma membrane]
Inferred From
FRS2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_010803404.1
,
XP_581582.1
,
XP_010826024.1
,
XP_010803405.1
,
XP_010826025.1
,
XP_002687431.1
OpenTargets
ENSG00000166225
Ensembl
ENSBTAG00000019155
,
ENSBTAT00000025495
,
ENSBTAP00000025495
VGNC
29120
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