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PIK3R4 [cytosol]
Stable Identifier
R-BTA-188010
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
PIK3R4, A6QLW1
Locations in the PathwayBrowser
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex (Bos taurus)
AMBRA1:DYNLL1,DYNLL2:BECN1 complex [cytosol] (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Autophagosome maturation (Bos taurus)
UVRAG complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
BECN1 complex:p-AMBRA1:DYNLL1,DYNLL2 [cytosol] (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Beclin-1 complex phosphorylates PtdIns (Bos taurus)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Beclin-1 complex translocates to the ER (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Beclin-1 complex [endoplasmic reticulum membrane] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
The phagophore extends from the PIP3-enriched structure (Bos taurus)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [phagophore assembly site membrane] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
ULK1 phosphorylates AMBRA1:BECN1 complex (Bos taurus)
AMBRA1:DYNLL1,DYNLL2:BECN1 complex [cytosol] (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
BECN1 complex:p-AMBRA1:DYNLL1,DYNLL2 [cytosol] (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
ULK1 phosphorylates Beclin-1 (Bos taurus)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Beclin-1 complex [endoplasmic reticulum membrane] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
Rab5-mediated recruitment of class III PI3K to TLR9 (Bos taurus)
PI3K class III [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
activated TLR9:PI3K class III [cytosol] (Bos taurus)
PI3K class III [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Phospholipid metabolism (Bos taurus)
PI Metabolism (Bos taurus)
Synthesis of PIPs at the Golgi membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Bos taurus)
PIK3C2A/3 [cytosol] (Bos taurus)
PIK3C3:Mn2+:PIK3R4:Mn2+ [cytosol] (Bos taurus)
PIK3R4:Mn2+ [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Synthesis of PIPs at the early endosome membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Bos taurus)
PIK3C2A/3 [cytosol] (Bos taurus)
PIK3C3:Mn2+:PIK3R4:Mn2+ [cytosol] (Bos taurus)
PIK3R4:Mn2+ [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Synthesis of PIPs at the late endosome membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Bos taurus)
PIK3C2A/3 [cytosol] (Bos taurus)
PIK3C3:Mn2+:PIK3R4:Mn2+ [cytosol] (Bos taurus)
PIK3R4:Mn2+ [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by Insulin receptor (Bos taurus)
Insulin receptor signalling cascade (Bos taurus)
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Bos taurus)
PI3K-containing complexes [cytosol] (Bos taurus)
activated TLR9:PI3K class III [cytosol] (Bos taurus)
PI3K class III [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Bos taurus)
IGF1R signaling cascade (Bos taurus)
IRS-related events triggered by IGF1R (Bos taurus)
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Bos taurus)
PI3K-containing complexes [cytosol] (Bos taurus)
activated TLR9:PI3K class III [cytosol] (Bos taurus)
PI3K class III [cytosol] (Bos taurus)
PIK3R4 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A6QLW1
Gene Names
PIK3R4
Reference Genes
BioGPS Gene:507414 PIK3R4
ENSEMBL:ENSBTAG00000020787.5
KEGG:bta:507414 PIK3R4
Monarch:507414 PIK3R4
NCBI Gene:507414 PIK3R4
UCSC:A6QLW1 PIK3R4
Reference Transcript
RefSeq:NM_001100314.2 PIK3R4
Participates
as a component of
PI3K class III [cytosol] (Bos taurus)
PIK3R4:Mn2+ [cytosol] (Bos taurus)
UVRAG complex [cytosol] (Bos taurus)
Beclin-1 complex [endoplasmic reticulum membrane] (Bos taurus)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [phagophore assembly site membrane] (Bos taurus)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Bos taurus)
BECN1 complex [cytosol] (Bos taurus)
Other forms of this molecule
PIK3R4 [phagocytic vesicle membrane]
Inferred From
PIK3R4 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001093784.1
VGNC
32895
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