Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
POT1 [nucleoplasm]
Stable Identifier
R-BTA-174890
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
POT1, E1BGK3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Chromosome Maintenance (Bos taurus)
Telomere Maintenance (Bos taurus)
Extension of Telomeres (Bos taurus)
Telomere C-strand (Lagging Strand) Synthesis (Bos taurus)
Disassociation of Processive Complex and Completed Telomere End (Bos taurus)
Extended And Processed Telomere End [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Polymerase switching on the C-strand of the telomere (Bos taurus)
Formation of Processive Complex on the C-strand of the telomere (Bos taurus)
Processive complex loaded on telomere [nucleoplasm] (Bos taurus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Bos taurus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Bos taurus)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive synthesis on the C-strand of the telomere (Bos taurus)
Formation of C-strand Okazaki fragments (Bos taurus)
Processive complex loaded on telomere [nucleoplasm] (Bos taurus)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Formation of the Flap Intermediate on the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Joining of adjacent Okazaki fragments of the C-strand (Bos taurus)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Removal of the Flap Intermediate from the C-strand (Bos taurus)
RPA binds to the Flap on the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Recruitment of DNA2 endonuclease to the C strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Removal of remaining Flap from the C-strand (Bos taurus)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomere C-strand synthesis initiation (Bos taurus)
DNA polymerase:primase binds G-strand of the telomere (Bos taurus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Bos taurus)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Bos taurus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Bos taurus)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomere Extension By Telomerase (Bos taurus)
Alignment Of The RNA Template On The Telomeric Chromosome End (Bos taurus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
CDK2:CCNA phosphorylates TERF2 (Bos taurus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Bos taurus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Disassociation of Telomerase RNP and the Chromosome End (Bos taurus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Elongation Of The Telomeric Chromosome End (Bos taurus)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Elongation of Extended Telomeric Chromosome End (Bos taurus)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
PP6-PPP6R3 dephosphorylates TERF2 (Bos taurus)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Bos taurus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Bos taurus)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Bos taurus)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Inhibition of DNA recombination at telomere (Bos taurus)
Histone H3.3 deposition at telomere (Bos taurus)
Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] (Bos taurus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Packaging Of Telomere Ends (Bos taurus)
Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Bos taurus)
Extended And Processed Telomere End [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
DNA Damage/Telomere Stress Induced Senescence (Bos taurus)
Telomere shortening during replicative exhaustion (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
DNA Repair (Bos taurus)
Base Excision Repair (Bos taurus)
Base-Excision Repair, AP Site Formation (Bos taurus)
Depurination (Bos taurus)
Cleavage of the damaged purine (Bos taurus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Bos taurus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Recognition and association of DNA glycosylase with site containing an affected purine (Bos taurus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
POT1 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BGK3
Gene Names
POT1
Reference Genes
ENSEMBL:ENSBTAG00000013180.6
UCSC:E1BGK3 POT1
Other Identifiers
511292
GO:0000781
GO:0000783
GO:0003677
GO:0005654
GO:0007004
GO:0010521
GO:0016233
GO:0017151
GO:0032200
GO:0032202
GO:0032210
GO:0032211
GO:0032212
GO:0032508
GO:0042162
GO:0043047
GO:0060383
GO:0061820
GO:0061821
GO:0070187
GO:0070200
GO:0098505
GO:0098772
GO:1905773
GO:1990955
GO:2001032
Participates
as a component of
AP-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Bos taurus)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
Shelterin complex [nucleoplasm] (Bos taurus)
as an output of
Telomere shortening during replicative exhaustion (Bos taurus)
as an input of
Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Bos taurus)
Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Bos taurus)
Inferred From
POT1 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAT00000017541
,
ENSBTAP00000017541
VGNC
33172
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text