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phosphorylated anaphase promoting complex (APC/C) [cytosol]
Stable Identifier
R-BTA-174191
Type
Complex
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
Mitotic Spindle Checkpoint (Bos taurus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Bos taurus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Bos taurus)
Binding of the MCC complex to the APC/C complex (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Separation of Sister Chromatids (Bos taurus)
Association of Securin with Cdc20:APC/C complex (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
CDC20:p-APC/C:PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Degradation of multiubiquitinated Securin (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Bos taurus)
CDC20:p-APC/C:PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Regulation of mitotic cell cycle (Bos taurus)
APC/C-mediated degradation of cell cycle proteins (Bos taurus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Bos taurus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Degradation of multiubiquitinated cell cycle proteins (Bos taurus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Bos taurus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Bos taurus)
APC/C:Cdc20 mediated degradation of Cyclin B (Bos taurus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Degradation of multiubiquitinated Cyclin B (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Bos taurus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
APC/C:Cdc20 mediated degradation of Securin (Bos taurus)
Association of Securin with Cdc20:APC/C complex (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
CDC20:p-APC/C:PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Degradation of multiubiquitinated Securin (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Bos taurus)
CDC20:p-APC/C:PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Bos taurus)
APC-Cdc20 mediated degradation of Nek2A (Bos taurus)
Association of Nek2A with MCC:APC/C (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Nek2A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Degradation of multiubiquitinated Nek2A (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Multiubiquitinated Nek2A [cytosol] (Bos taurus)
Nek2A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Multiubiquitination of Nek2A (Bos taurus)
Multiubiquitinated Nek2A [cytosol] (Bos taurus)
Nek2A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Nek2A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Bos taurus)
Association of Cyclin A with the APC/C (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Degradation multiubiquitinated Cyclin A (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Bos taurus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Bos taurus)
Association of Cdh1 with the APC/C (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Dissociation of Cdc20 from APC/C complex (Bos taurus)
CDC20:p-APC/C [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
Regulation of APC/C activators between G1/S and early anaphase (Bos taurus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Bos taurus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Bos taurus)
Binding of the MCC complex to the APC/C complex (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
S Phase (Bos taurus)
Synthesis of DNA (Bos taurus)
Switching of origins to a post-replicative state (Bos taurus)
CDK-mediated phosphorylation and removal of Cdc6 (Bos taurus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
DNA Replication (Bos taurus)
Synthesis of DNA (Bos taurus)
Switching of origins to a post-replicative state (Bos taurus)
CDK-mediated phosphorylation and removal of Cdc6 (Bos taurus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ANAPC1 [cytosol]
(Bos taurus)
ANAPC10 [cytosol]
(Bos taurus)
ANAPC15 [cytosol]
(Bos taurus)
ANAPC16 [cytosol]
(Bos taurus)
ANAPC2 [cytosol]
(Bos taurus)
ANAPC4 [cytosol]
(Bos taurus)
ANAPC5 [cytosol]
(Bos taurus)
ANAPC7 [cytosol]
(Bos taurus)
CDC16 [cytosol]
(Bos taurus)
CDC23 [cytosol]
(Bos taurus)
CDC26 [cytosol]
(Bos taurus)
CDC27 [cytosol]
(Bos taurus)
Homologues of ANAPC11 [cytosol]
(Bos taurus)
UBE2C [cytosol]
(Bos taurus)
UBE2D1 [cytosol]
(Bos taurus)
UBE2E1 [cytosol]
(Bos taurus)
UBE2S [cytosol]
(Bos taurus)
Participates
as an input of
Association of Cdh1 with the APC/C (Bos taurus)
Binding of the MCC complex to the APC/C complex (Bos taurus)
as an output of
Dissociation of Cdc20 from APC/C complex (Bos taurus)
as a component of
CDC20:p-APC/C [cytosol] (Bos taurus)
phospho-APC/C:Cdh1 complex [cytosol] (Bos taurus)
MCC:APC/C complex [cytosol] (Bos taurus)
Inferred From
phosphorylated anaphase promoting complex (APC/C) [cytosol]
(Homo sapiens)
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