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IRAK4 [cytosol]
Stable Identifier
R-BTA-166081
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
Q1RMT8
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Bos taurus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
IRAK4 is activated by autophosphorylation (Bos taurus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Bos taurus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
The Interleukin 1 receptor complex binds Tollip (Bos taurus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer:TOLLIP [plasma membrane] (Bos taurus)
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 (Bos taurus)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Bos taurus)
IRAK4: Pellino-1,2,3 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Bos taurus)
IRAK4: p-Pellino-1,2,3 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Bos taurus)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Bos taurus)
IRAK4: Pellino-1,2,3 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
p-2S,S376,T,T209,T387-IRAK1, IRAK4 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Bos taurus)
IRAK1:Pellino:E2 complexes [cytosol] (Bos taurus)
IRAK4: p-Pellino-1,2,3:UBE2N:UBE2V1:K63polyUb [cytosol] (Bos taurus)
IRAK4: p-Pellino-1,2,3 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino [cytosol] (Bos taurus)
IRAK4: p-Pellino-1,2,3 [cytosol] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Bos taurus)
IRAK4 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q1RMT8
Reference Genes
BioGPS Gene:533692
ENSEMBL:ENSBTAG00000021105
KEGG:bta:533692
Monarch:533692
NCBI Gene:533692
UCSC:Q1RMT8
Reference Transcript
RefSeq:XM_005206426.5
RefSeq:NM_001075998.1
Other Identifiers
533692
Bt.9250.1.A1_at
Bt.9250.2.S1_at
GO:0000287
GO:0002376
GO:0002446
GO:0003824
GO:0004672
GO:0004674
GO:0005149
GO:0005524
GO:0006468
GO:0007165
GO:0009986
GO:0016301
GO:0016740
GO:0019221
GO:0019901
GO:0034142
GO:0038061
GO:0038172
GO:0043123
GO:0048870
GO:0070498
GO:0140096
GO:1990266
Participates
as a member of
p-2S,S376,T,T209,T387-IRAK1, IRAK4 [cytosol] (Bos taurus)
as a component of
IL1R1:IL1:IL1RAP:IRAK4:MYD88 dimer [plasma membrane] (Bos taurus)
IRAK4: p-Pellino-1,2,3 [cytosol] (Bos taurus)
IRAK4: Pellino-1,2,3 [cytosol] (Bos taurus)
IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Bos taurus)
as an input of
IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Bos taurus)
Other forms of this molecule
phospho-p-T342,T345,S346-IRAK4 [cytosol]
Inferred From
IRAK4 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001069466.1
,
XP_005206483.1
ENSEMBL
ENSBTAP00000028115
,
ENSBTAG00000021105
,
ENSBTAT00000028115
VGNC
30268
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