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F2 [plasma membrane]
Stable Identifier
R-BTA-140809
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
F2(364-622), A0A452DI66
Locations in the PathwayBrowser
Expand all
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
activated thrombin:thrombomodulin [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
Coagulation pathway (Bos taurus)
Amplification and propagation of coagulation cascade (Bos taurus)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
Fibrin formation (Bos taurus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
Regulation of clotting cascade (Bos taurus)
Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
activated thrombin:thrombomodulin [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) + antithrombin III:heparan sulfate -> thrombin:antithrombin III:heparan sulfate (Bos taurus)
thrombin:SERPINC1:HSPGs [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Bos taurus)
activated thrombin:thrombomodulin [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
thrombin:antithrombin III:heparan sulfate -> thrombin:cleaved antithrombin III:heparan sulfate (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
thrombin:SERPINC1:HSPGs [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
thrombin:cleaved SERPINC1:HSPGs [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
thrombin:cleaved SERPINC1:HSPGs-> thrombin:cleaved SERPINC1 + HSPGs (Bos taurus)
thrombin:cleaved SERPINC1:HSPGs [plasma membrane] (Bos taurus)
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
F2 [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A452DI66
Gene Names
F2
Reference Genes
ENSEMBL:ENSBTAG00000007148.6
UCSC:A0A452DI66 F2
Other Identifiers
280685
Bt.470.1.S1_at
GO:0001530
GO:0002376
GO:0004175
GO:0004252
GO:0005102
GO:0005509
GO:0005576
GO:0005615
GO:0006508
GO:0006953
GO:0006954
GO:0007166
GO:0007186
GO:0007596
GO:0007599
GO:0008201
GO:0008233
GO:0008236
GO:0008284
GO:0008289
GO:0008360
GO:0009611
GO:0009897
GO:0010468
GO:0016787
GO:0030168
GO:0030194
GO:0030195
GO:0030307
GO:0032024
GO:0032967
GO:0042730
GO:0045861
GO:0048018
GO:0048712
GO:0050878
GO:0051281
GO:0051480
GO:0051604
GO:0051838
GO:0051897
GO:0061844
GO:0070053
GO:0070493
GO:0070945
GO:0072378
GO:0098542
GO:0098772
GO:1900016
GO:1900182
GO:1900738
GO:1990806
GO:2000379
Participates
as a component of
activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
Other forms of this molecule
F2 [Golgi lumen]
F2 [Golgi lumen]
F2 [Golgi lumen]
F2 [endoplasmic reticulum lumen]
F2 [endoplasmic reticulum lumen]
F2 [plasma membrane]
F2 [extracellular region]
F2 [extracellular region]
F2 [extracellular region]
F2 [extracellular region]
Inferred From
F2(364-622) [plasma membrane]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAP00000009406
,
ENSBTAT00000009406
,
ENSBTAG00000007148
VGNC
28682
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