Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GAG [plasma membrane]
Stable Identifier
R-ALL-977180
Type
Chemical Compound [SimpleEntity]
Compartment
plasma membrane
Synonyms
glycosaminoglycan
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Formation of Fibrin Clot (Clotting Cascade) (Bos taurus)
Common Pathway of Fibrin Clot Formation (Bos taurus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Bos taurus)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Bos taurus)
GAG [plasma membrane]
factor V -> factor Va + factor V activation peptide (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Bos taurus)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
Hemostasis (Canis familiaris)
Formation of Fibrin Clot (Clotting Cascade) (Canis familiaris)
Common Pathway of Fibrin Clot Formation (Canis familiaris)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Canis familiaris)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Canis familiaris)
GAG [plasma membrane]
factor V -> factor Va + factor V activation peptide (Canis familiaris)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Canis familiaris)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
Hemostasis (Danio rerio)
Formation of Fibrin Clot (Clotting Cascade) (Danio rerio)
Common Pathway of Fibrin Clot Formation (Danio rerio)
SERPINA5 binds activated protein C (Danio rerio)
GAG [plasma membrane]
Hemostasis (Gallus gallus)
Formation of Fibrin Clot (Clotting Cascade) (Gallus gallus)
Common Pathway of Fibrin Clot Formation (Gallus gallus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Gallus gallus)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
factor V -> factor Va + factor V activation peptide (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Gallus gallus)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Common Pathway of Fibrin Clot Formation (Homo sapiens)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Homo sapiens)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Homo sapiens)
GAG [plasma membrane]
factor V -> factor Va + factor V activation peptide (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Homo sapiens)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
Amyloid fibrils have additional components (Homo sapiens)
GAG [plasma membrane]
Amyloid fibrils [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
Hemostasis (Mus musculus)
Formation of Fibrin Clot (Clotting Cascade) (Mus musculus)
Common Pathway of Fibrin Clot Formation (Mus musculus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Mus musculus)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Mus musculus)
GAG [plasma membrane]
factor V -> factor Va + factor V activation peptide (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Mus musculus)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
Hemostasis (Rattus norvegicus)
Formation of Fibrin Clot (Clotting Cascade) (Rattus norvegicus)
Common Pathway of Fibrin Clot Formation (Rattus norvegicus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Rattus norvegicus)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Rattus norvegicus)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Rattus norvegicus)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
Hemostasis (Sus scrofa)
Formation of Fibrin Clot (Clotting Cascade) (Sus scrofa)
Common Pathway of Fibrin Clot Formation (Sus scrofa)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Sus scrofa)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Sus scrofa)
GAG [plasma membrane]
factor V -> factor Va + factor V activation peptide (Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Sus scrofa)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
Hemostasis (Xenopus tropicalis)
Formation of Fibrin Clot (Clotting Cascade) (Xenopus tropicalis)
Common Pathway of Fibrin Clot Formation (Xenopus tropicalis)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Xenopus tropicalis)
GAG [plasma membrane]
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Xenopus tropicalis)
GAG [plasma membrane]
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Xenopus tropicalis)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
Intrinsic Pathway of Fibrin Clot Formation (Xenopus tropicalis)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Xenopus tropicalis)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
External Reference Information
External Reference
glycosaminoglycan [ChEBI:18085]
Participates
as a component of
Amyloid fibrils [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Drosophila melanogaster)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Caenorhabditis elegans)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Danio rerio)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
as an input of
Amyloid fibrils have additional components (Homo sapiens)
This entity regulates
Positively
SERPINA5 binds activated protein C
(Xenopus tropicalis)
SERPINA5 binds activated protein C
(Danio rerio)
SERPINA5 binds activated protein C
(Bos taurus)
SERPINA5 binds activated protein C
(Homo sapiens)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Xenopus tropicalis)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Bos taurus)
SERPINA5 binds activated protein C
(Sus scrofa)
SERPINA5 binds activated protein C
(Canis familiaris)
SERPINA5 binds activated protein C
(Rattus norvegicus)
SERPINA5 binds activated protein C
(Mus musculus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Gallus gallus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Sus scrofa)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Canis familiaris)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Rattus norvegicus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Mus musculus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
![GAG [plasma membrane] icon](/icon/R-ICO-012781.svg){kind=icon}
