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GAG [plasma membrane]
Stable Identifier
R-ALL-977180
Type
Chemical Compound [SimpleEntity]
Compartment
plasma membrane
Synonyms
glycosaminoglycan
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Coagulation pathway (Bos taurus)
Amplification and propagation of coagulation cascade (Bos taurus)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
Fibrin formation (Bos taurus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Bos taurus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
Regulation of clotting cascade (Bos taurus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Bos taurus)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Bos taurus)
GAG [plasma membrane]
Hemostasis (Canis familiaris)
Coagulation pathway (Canis familiaris)
Amplification and propagation of coagulation cascade (Canis familiaris)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Canis familiaris)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
Fibrin formation (Canis familiaris)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Canis familiaris)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
Regulation of clotting cascade (Canis familiaris)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Canis familiaris)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Canis familiaris)
GAG [plasma membrane]
Hemostasis (Danio rerio)
Coagulation pathway (Danio rerio)
Amplification and propagation of coagulation cascade (Danio rerio)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Danio rerio)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Danio rerio)
SERPINE2:GAG [plasma membrane] (Danio rerio)
GAG [plasma membrane]
Fibrin formation (Danio rerio)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Danio rerio)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Danio rerio)
SERPINE2:GAG [plasma membrane] (Danio rerio)
GAG [plasma membrane]
Regulation of clotting cascade (Danio rerio)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Danio rerio)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Danio rerio)
SERPINE2:GAG [plasma membrane] (Danio rerio)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Danio rerio)
SERPINE2:GAG [plasma membrane] (Danio rerio)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Danio rerio)
GAG [plasma membrane]
Hemostasis (Gallus gallus)
Coagulation pathway (Gallus gallus)
Amplification and propagation of coagulation cascade (Gallus gallus)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
Fibrin formation (Gallus gallus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Gallus gallus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
Regulation of clotting cascade (Gallus gallus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Gallus gallus)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Gallus gallus)
GAG [plasma membrane]
Hemostasis (Homo sapiens)
Coagulation pathway (Homo sapiens)
Amplification and propagation of coagulation cascade (Homo sapiens)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
Fibrin formation (Homo sapiens)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Homo sapiens)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
Regulation of clotting cascade (Homo sapiens)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Homo sapiens)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Homo sapiens)
GAG [plasma membrane]
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
Amyloid fibrils have additional components (Homo sapiens)
GAG [plasma membrane]
Amyloid fibrils [plasma membrane] (Homo sapiens)
GAG [plasma membrane]
Hemostasis (Mus musculus)
Coagulation pathway (Mus musculus)
Amplification and propagation of coagulation cascade (Mus musculus)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
Fibrin formation (Mus musculus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
Regulation of clotting cascade (Mus musculus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Mus musculus)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Mus musculus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Mus musculus)
GAG [plasma membrane]
Hemostasis (Rattus norvegicus)
Coagulation pathway (Rattus norvegicus)
Amplification and propagation of coagulation cascade (Rattus norvegicus)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
Fibrin formation (Rattus norvegicus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
Regulation of clotting cascade (Rattus norvegicus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Rattus norvegicus)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Rattus norvegicus)
GAG [plasma membrane]
Hemostasis (Sus scrofa)
Coagulation pathway (Sus scrofa)
Amplification and propagation of coagulation cascade (Sus scrofa)
factor V -> factor Va + factor V activation peptide (thrombin catalyst) (Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
Fibrin formation (Sus scrofa)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Sus scrofa)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
Regulation of clotting cascade (Sus scrofa)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Sus scrofa)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Sus scrofa)
GAG [plasma membrane]
Hemostasis (Xenopus tropicalis)
Coagulation pathway (Xenopus tropicalis)
Amplification and propagation of coagulation cascade (Xenopus tropicalis)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Xenopus tropicalis)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
Fibrin formation (Xenopus tropicalis)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Xenopus tropicalis)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
Regulation of clotting cascade (Xenopus tropicalis)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Xenopus tropicalis)
GAG [plasma membrane]
Protease nexin-1 (SERPINE2) is a specific and extremely efficient inhibitor of thrombin (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
GAG [plasma membrane]
SERPINA5 binds activated protein C (Xenopus tropicalis)
GAG [plasma membrane]
External Reference Information
External Reference
glycosaminoglycan [ChEBI:18085]
Participates
as a component of
Amyloid fibrils [plasma membrane] (Homo sapiens)
SERPINE2:GAG [plasma membrane] (Mus musculus)
SERPINE2:GAG [plasma membrane] (Canis familiaris)
SERPINE2:GAG [plasma membrane] (Danio rerio)
SERPINE2:GAG [plasma membrane] (Xenopus tropicalis)
SERPINE2:GAG [plasma membrane] (Sus scrofa)
SERPINE2:GAG [plasma membrane] (Drosophila melanogaster)
SERPINE2:GAG [plasma membrane] (Caenorhabditis elegans)
SERPINE2:GAG [plasma membrane] (Gallus gallus)
SERPINE2:GAG [plasma membrane] (Bos taurus)
SERPINE2:GAG [plasma membrane] (Rattus norvegicus)
SERPINE2:GAG [plasma membrane] (Homo sapiens)
as an input of
Amyloid fibrils have additional components (Homo sapiens)
This entity regulates
Positively
SERPINA5 binds activated protein C
(Gallus gallus)
SERPINA5 binds activated protein C
(Homo sapiens)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Gallus gallus)
SERPINA5 binds activated protein C
(Xenopus tropicalis)
SERPINA5 binds activated protein C
(Danio rerio)
SERPINA5 binds activated protein C
(Sus scrofa)
SERPINA5 binds activated protein C
(Bos taurus)
SERPINA5 binds activated protein C
(Canis familiaris)
SERPINA5 binds activated protein C
(Rattus norvegicus)
SERPINA5 binds activated protein C
(Mus musculus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Xenopus tropicalis)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Danio rerio)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Sus scrofa)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Bos taurus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Canis familiaris)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Rattus norvegicus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Mus musculus)
Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa)
(Homo sapiens)
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